Progress in Inflammation Research

Heat Shock Proteins and Inflammation

Editors: Eden, Willem van (Ed.)

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  • ISBN 978-3-0348-8028-2
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About this book

Heat shock proteins have received ample interest by immunologists over recent years. Initially they were found to be dominantly immunogenic microbial antigens. The connection to inflammation was established when it was uncovered that T cells reactive to hsp60 of mycobacteria had a crucial role in the induction and, more interestingly, regulation of experimental arthritis. Since then, the raised presence of immunity to hsp in virtually all conditions of inflammation, including autoimmune diseases, transplant rejection and atherosclerosis, has emphasised the critical significance of immunity to hsp in inflammatory diseases. Recently, first trials with hsp peptides were undertaken and reported in type I diabetes and in arthritis. As this has stimulated a wide interest in this particular field the book aims at giving an update of these exciting current developments and to provide the basis for understanding the mode of action of hsp based immunotherapeutic interventions.  This will include aspects of specific adaptive immunity and aspects of innate immunity.

The book has its focus on immunity to hsp and its impact on the regulation of inflammation. It is of interest to biologists, immunologists, microbiologists and other researchers, but also clinicians interested in the rapidly evolving field of immune-interventions.

Table of contents (17 chapters)

  • HSP60 and the regulation of inflammation: Physiological and pathological

    Cohen, Irun R. (et al.)

    Pages 1-13

  • Heat shock proteins and suppression of inflammation

    Eden, Willem (et al.)

    Pages 15-31

  • Heat shock proteins in immune response

    Basu, Sreyashi (et al.)

    Pages 33-42

  • Heat shock protein-mediated activation of innate immune cells

    Costa, Clarissa U. I. Prazeres (et al.)

    Pages 43-54

  • Eukaryotic HSP60: A “danger signal” for T- and natural killer cells

    Bonin, Arne (et al.)

    Pages 55-67

Buy this book

eBook $169.00
price for USA (gross)
  • ISBN 978-3-0348-8028-2
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $299.00
price for USA
  • ISBN 978-3-7643-6932-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $219.00
price for USA
  • ISBN 978-3-0348-9410-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Heat Shock Proteins and Inflammation
Editors
  • Willem van Eden
Series Title
Progress in Inflammation Research
Copyright
2003
Publisher
Birkhäuser Basel
Copyright Holder
Springer Basel AG
eBook ISBN
978-3-0348-8028-2
DOI
10.1007/978-3-0348-8028-2
Hardcover ISBN
978-3-7643-6932-3
Softcover ISBN
978-3-0348-9410-4
Edition Number
1
Number of Pages
XIII, 280
Topics