Progress in Inflammation Research

Antirheumatic Therapy: Actions and Outcomes

Editors: Day, R.O., Furst, D.E., Riel, P.L.C.M. van, Bresnihan, B. (Eds.)

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About this book

Our goal for this book is to examine the contemporary therapy of rheumatoid arthritis (RA) from the increasingly important perspective of impact upon quality of life, costs and long-term health outcomes. For too long the focus has been on short­ term, symptomatic, and surrogate indicator outcomes. Yet RA is a life-long disor­ der with the majority of impact on an individual patient many years following onset. Further, even in the short-term, researchers and rheumatologists have tended to emphasize measurements of disease activity such as joint counts, ESR and physi­ cian's opinion as to the amount of disease activity present. It is only relatively recently that measures of structural damage, quality of life and impact on broad domains of health have been given increasing emphasis. Also, the significance of early treatment of RA in order to optimise long-term outcomes has a relatively short history [1]. We have been focussed on the disease processes as surrogates for long­ term outcomes. Until the short-term process measures are validated as surrogates of long-term effects we should also turn our attention to outcomes of disease and the impact of our management on those outcomes [2). Inour view, this book is especially timely. We are at the dawn of a revolution in the management of RA and other complex immunological inflammatory disorders because their molecular, genetic and environmental mechanisms are being unrav­ elled. Inthe process, we are revealing a substantial number of novel and significant targets for pharmacotherapy.

Table of contents (17 chapters)

  • Medicinal chemistry of the disease modifying anti-rheumatic drugs

    Graham, Garry G.

    Pages 1-24

  • Targeting DMARD therapy

    Suarez-Almazor, Maria E.

    Pages 25-47

  • Pharmacoeconomic properties of disease-modifying antirheumatic drugs

    Maetzel, Andreas (et al.)

    Pages 49-67

  • Future molecular targets

    Keystone, Edward C. (et al.)

    Pages 69-80

  • Hydroxychloroquine

    Bothwell, Beau (et al.)

    Pages 81-92

Buy this book

eBook $229.00
price for USA (gross)
  • ISBN 978-3-7643-7726-7
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $299.00
price for USA
  • ISBN 978-3-7643-6595-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Antirheumatic Therapy: Actions and Outcomes
Editors
  • Richard O. Day
  • Daniel E. Furst
  • Piet L.C.M. van Riel
  • Barry Bresnihan
Series Title
Progress in Inflammation Research
Copyright
2005
Publisher
Birkhäuser Basel
Copyright Holder
Birkhäuser Basel
eBook ISBN
978-3-7643-7726-7
DOI
10.1007/978-3-7643-7726-7
Hardcover ISBN
978-3-7643-6595-0
Edition Number
1
Number of Pages
XIII, 343
Topics