Experientia Supplementum

DNA Methylation

Molecular Biology and Biological Significance

Authors: Jost, J., Saluz, H.

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About this book

The occurrence of 5-methylcytosine in DNA was first described in 1948 by Hotchkiss (see first chapter). Recognition of its possible physiologi­ cal role in eucaryotes was first suggested in 1964 by Srinivasan and Borek (see first chapter). Since then work in a great many laboratories has established both the ubiquity of 5-methylcytosine and the catholicity of its possible regulatory function. The explosive increase in the number of publications dealing with DNA methylation attests to its importance and makes it impossible to write a comprehensive coverage of the literature within the scope of a general review. Since the publication of the 3 most recent books dealing with the subject (DNA methylation by Razin A. , Cedar H. and Riggs A. D. , 1984 Springer Verlag; Molecular Biology of DNA methylation by Adams R. L. P. and Burdon R. H. , 1985 Springer Verlag; Nucleic Acids Methylation, UCLA Symposium suppl. 128, 1989) considerable progress both in the techniques and results has been made in the field of DNA methylation. Thus we asked several authors to write chapters dealing with aspects of DNA methyla­ tion in which they are experts. This book should be most useful for students, teachers as well as researchers in the field of differentiation and gene regulation. We are most grateful to all our colleagues who were willing to spend much time and effort on the publication of this book. We also want to express our gratitude to Yan Chim Jost for her help in preparing this book.

Table of contents (24 chapters)

  • A Chronicle of DNA methylation (1948–1975)

    Weissbach, Arthur

    Pages 1-10

  • Major techniques to study DNA methylation

    Saluz, Hanspeter (et al.)

    Pages 11-26

  • Methylation of cytosine influences the DNA structure

    Zacharias, Wolfgang

    Pages 27-38

  • Methylation of DNA in Prokaryotes

    Noyer-Weidner, Mario (et al.)

    Pages 39-108

  • Structure, function and regulation of mammalian DNA methyltransferase

    Leonhardt, Heinrich (et al.)

    Pages 109-119

Buy this book

eBook $69.99
price for USA (gross)
  • ISBN 978-3-0348-9118-9
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $99.00
price for USA
  • ISBN 978-3-7643-2778-1
  • Free shipping for individuals worldwide
  • This title is currently reprinting. You can pre-order your copy now.
Softcover $99.00
price for USA
  • ISBN 978-3-0348-9915-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
DNA Methylation
Book Subtitle
Molecular Biology and Biological Significance
Authors
Series Title
Experientia Supplementum
Series Volume
64
Copyright
1993
Publisher
Birkhäuser Basel
Copyright Holder
Birkhäuser Verlag
eBook ISBN
978-3-0348-9118-9
DOI
10.1007/978-3-0348-9118-9
Hardcover ISBN
978-3-7643-2778-1
Softcover ISBN
978-3-0348-9915-4
Series ISSN
1023-294X
Edition Number
1
Number of Pages
X, 572
Topics