Overview
Comprehensive approach to recent research results on disc de- and regeneration
Numerous 4c illustrations
Contributions of international authors
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Table of contents (26 chapters)
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Front Matter
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Biomechanical and Molecular Studies of the Intervertebral Disc
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Front Matter
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Intervertebral Disc Disease: Pathogenesis and Current Treatment Modalities
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Front Matter
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Keywords
About this book
The intervertebral disc is a complex structure that separates opposing vertebrae, permits a wide range of motion, and accommodates high biomechanical forces. Disc degeneration leads to a loss of function and is often associated with excruciating pain.
Written by leading scientists and clinicians, the first part of the book provides a review of the basic biology of the disc in health and disease. The second part considers strategies to mitigate the effects of disc degeneration and discusses the possibility of engineering replacement tissues. The final section is devoted to approaches to model normal development and elucidate the pathogenesis of degenerative disc disease using animal, organ and cell culture techniques.Â
The book bridges the gap between the basic and clinical sciences; the target audience includes basic scientists, orthopaedists and neurologists, while at the same time appealing to the needs of graduate students, medical students, interns and fellows.
Editors and Affiliations
About the editors
Irving M. Shapiro BDS, PhD
Makarand Risbud, Ph.D.
Division of Orthopaedic Research, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA, USA
Bibliographic Information
Book Title: The Intervertebral Disc
Book Subtitle: Molecular and Structural Studies of the Disc in Health and Disease
Editors: Irving M. Shapiro, Makarand V. Risbud
DOI: https://doi.org/10.1007/978-3-7091-1535-0
Publisher: Springer Vienna
eBook Packages: Medicine, Medicine (R0)
Copyright Information: Springer-Verlag Wien 2014
Hardcover ISBN: 978-3-7091-1534-3Published: 13 September 2013
Softcover ISBN: 978-3-7091-1943-3Published: 23 August 2016
eBook ISBN: 978-3-7091-1535-0Published: 02 September 2013
Edition Number: 1
Number of Pages: X, 446
Number of Illustrations: 88 b/w illustrations, 42 illustrations in colour
Topics: Surgical Orthopedics, Neurosurgery, Orthopedics