Stem Cell Aging: Mechanisms, Consequences, Rejuvenation

Editors: Geiger, Hartmut, Jasper, Heinrich, Florian, Maria Carolina (Eds.)

  • First comprehensive book on stem cell aging and rejuvenation
  • Depicts the mechanism of aging in different tissues
  • Covers model organisms and mammalian systems
  • Written by prominent experts in the field​
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Buy this book

eBook $139.00
price for USA (gross)
  • ISBN 978-3-7091-1232-8
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $179.00
price for USA
  • ISBN 978-3-7091-1231-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $179.00
price for USA
  • Customers within the U.S. and Canada please contact Customer Service at 1-800-777-4643, Latin America please contact us at +1-212-460-1500 (Weekdays 8:30am – 5:30pm ET) to place your order.
  • Due: November 4, 2016
  • ISBN 978-3-7091-1959-4
  • Free shipping for individuals worldwide
About this book

Aging of somatic stem cells reduces cell function and results in dysfunctional organs and tissues, making it an underlying cause of diseases associated with aging. It might even be the primary cause for age-associated attrition of tissue function in organs that heavily rely on stem cells for maintaining homeostasis, like the skin, blood and intestines. Understanding the molecular and cellular mechanisms involved is critical for developing approaches to attenuate stem cell aging and could pave the way for improved quality of life among the elderly. Written by highly prominent experts in the field, this book presents the current state of knowledge on these mechanisms. It offers insights into stem cell function, explains in detail the mechanisms of stem cell aging in model organisms as well as mammalian systems and describes related diseases and approaches to attenuating stem cell aging or achieving rejuvenation. The book is intended for all scientists and clinicians working with stem cells, aging mechanisms or age-related diseases.

About the authors

Hartmut Geiger studied chemistry and biochemistry at the Universities of Karlsruhe and Witten/Herdecke in Germany. He received his PhD from the Max-Planck-Institute for Immunobiology in Freiburg, Germany in 1999. From 1999 to 2002  he was scientific research fellow at the University of Kentucky, USA with expertise in stem cells, genetics and aging. From 2002 to 2008 he was Assistant Professor at the Division of Experimental Hematology, Cincinnati Children’s Hospital Medical Center, University of Cincinnati, USA. Since 2008 he has been Associate Professor at the University of Cincinnati, USA and Professor at the University of Ulm, Division of Dermatology and Allergic Diseases, Germany. His main research interest lies in the molecular biology of aging.

Reviews

“This book discusses the impact of aging on the many stem cell populations, the pathologies associated with the decline of stem cell functions, and the use of stem cells to attenuate stem cell aging. … The purpose is to provide a reference for researchers working in the field of healthy aging. The audience is clinicians and all scientists working in the field of aging, stem cells, and regenerative medicine.” (Michele Fornaro, Doody's Book Reviews, October, 2015)


Table of contents (16 chapters)

  • Stem Cell Aging: An Overview

    Jasper, Heinrich

    Pages 3-15

  • Aging in the Single-Celled Eukaryote, S. cerevisiae

    He, Chong (et al.)

    Pages 19-49

  • Germline Stem Cells and Their Roles in the Regulation of Organism Longevity

    Lin, Chih-chun Janet (et al.)

    Pages 51-70

  • Age-Related Changes to Drosophila m. Male Germline Stem Cells

    Toledano, Hila (et al.)

    Pages 71-84

  • Aging of Intestinal Stem Cells in Drosophila Melanogaster

    Biteau, Benoît

    Pages 85-104

Buy this book

eBook $139.00
price for USA (gross)
  • ISBN 978-3-7091-1232-8
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $179.00
price for USA
  • ISBN 978-3-7091-1231-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $179.00
price for USA
  • Customers within the U.S. and Canada please contact Customer Service at 1-800-777-4643, Latin America please contact us at +1-212-460-1500 (Weekdays 8:30am – 5:30pm ET) to place your order.
  • Due: November 4, 2016
  • ISBN 978-3-7091-1959-4
  • Free shipping for individuals worldwide
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Bibliographic Information

Bibliographic Information
Book Title
Stem Cell Aging: Mechanisms, Consequences, Rejuvenation
Editors
  • Hartmut Geiger
  • Heinrich Jasper
  • Maria Carolina Florian
Copyright
2015
Publisher
Springer-Verlag Wien
Copyright Holder
Springer-Verlag Wien
eBook ISBN
978-3-7091-1232-8
DOI
10.1007/978-3-7091-1232-8
Hardcover ISBN
978-3-7091-1231-1
Softcover ISBN
978-3-7091-1959-4
Edition Number
1
Number of Pages
XI, 354
Number of Illustrations and Tables
1 b/w illustrations, 32 illustrations in colour
Topics