Overview
Systematically reviews cell dedifferentiation and regenerative medicine
Reviews the relationship between cell dedifferentiation and the development of cancer and several other diseases
Offers detailed descriptions, from the cell dedifferentiation phenomenon to molecular mechanisms, to clinical applications in regenerative medicine
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Table of contents (12 chapters)
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Front Matter
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Back Matter
Keywords
About this book
This book focuses on the contribution of cell dedifferentiation to the regenerative process in all body systems, as well as its underlying molecular mechanisms and applications.
The book is divided into four parts, the first of which addresses the history of cell dedifferentiation and regenerative medicine. In turn, Part II compares three routes by which cells change their phenotype: dedifferentiation, transdifferentiation, and reprogramming. Part III includes an extensive review of cell dedifferentiation events in all nine body systems for lower organisms and mammalians, respectively. The final part reviews the relationship between cell dedifferentiation and the development of cancer and several other diseases, while also outlining the prospects of and future research directions in cell dedifferentiation and regenerative medicine.
The main purpose of the book is to underline the importance of cell dedifferentiation in stem cell and regenerative medicine by providing a systematical review of dedifferentiation in all body systems, together with the latest reliable evidence.Â
Authors and Affiliations
About the authors
Xiaobing Fu is a professor and director of the Key Laboratory of Wound Repair and Regenerative Medicine of PLA, The College of Life Sciences of the PLA General Hospital, Beijing, China. Professor Fu is also an academician of Chinese Academy of Engineering (Division of Medicine and Health). Andong Zhao is a doctor from Tianjin Medical University, Tianjin, China. Tian Hu is a doctor at the School of medicine, Nankai University, China.
Bibliographic Information
Book Title: Cellular Dedifferentiation and Regenerative Medicine
Authors: Xiaobing Fu, Andong Zhao, Tian Hu
DOI: https://doi.org/10.1007/978-3-662-56179-9
Publisher: Springer Berlin, Heidelberg
eBook Packages: Medicine, Medicine (R0)
Copyright Information: Springer-Verlag GmbH Germany 2018
Hardcover ISBN: 978-3-662-56177-5Published: 20 February 2018
Softcover ISBN: 978-3-662-57257-3Published: 04 June 2019
eBook ISBN: 978-3-662-56179-9Published: 09 February 2018
Edition Number: 1
Number of Pages: XII, 291
Number of Illustrations: 6 b/w illustrations, 21 illustrations in colour
Topics: Traumatic Surgery, Dermatology, Regenerative Medicine/Tissue Engineering