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Management of Periprosthetic Joint Infection

A global perspective on diagnosis, treatment options, prevention strategies and their economic impact

Editors: Kühn, Klaus-Dieter (Ed.)

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eBook $84.99
price for USA (gross)
  • ISBN 978-3-662-54469-3
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $109.00
price for USA
  • Customers within the U.S. and Canada please contact Customer Service at 1-800-777-4643, Latin America please contact us at +1-212-460-1500 (Weekdays 8:30am – 5:30pm ET) to place your order.
  • Due: December 21, 2017
  • ISBN 978-3-662-54468-6
  • Free shipping for individuals worldwide
About this book

Periprosthetic joint infection (PJI) is among the most serious complications in the field of endoprosthetics. The number of PJIs is increasing worldwide and poses a real interdisciplinary challenge for everyone involved. For the patient concerned, it is necessary to promptly work out an adequate therapy solution to fight off the infection. Both the clinical experience of the surgeon and the proper diagnostic processes are prerequisite for the reliable detection and identification of an infection. The microbiologist is responsible for identifying the causative germs by screening the patient’s synovial fluid and tissue samples. Based on the findings and subsequent resistance testing, the infectious disease specialist can recommend the appropriate antibiotic therapy. Furthermore, the clinical pharmacist is consulted regularly throughout the therapy to discuss the risk of potential drug interactions. The surgeon will proceed with the revision surgery, following defined algorithms. Adequate radical debridement of infected and necrotic surrounding tissue is the most important step towards a successful cure of the infection. Accompanying the surgery, anti-infective agents are given systemically and locally. While systemic application of anti-infectives mainly reduces the number of haematogenic-spreading planktonic germs, local application immediately forms a colonization barrier and protects the implant from sessile biofilm formation. Concurrently, antibiotics are actively released from the implant, resulting in local germ reduction. Thus, local agents are embedded in the concept of surgical PJI treatment as a reliable adjuvant measure and they sustainably support the successful outcome. In one-stage procedures, local agents are released from specialized antibiotic-loaded bone cements, while in two- or multi-stage procedures, local agents are released from corresponding temporary spacers (interim prostheses). Even from an economic standpoint, the combination of systemic and local agent application is meaningful. Furthermore, there are some interesting trends towards the coating of metallic implants to protect against biofilm formation on the implant surface.

On the basis of their personal experience, specialists from all over the world present, explain and discuss preventive approaches, appropriate diagnostic strategies for detection, reproducible effective surgical treatments  as well as the economic impact of PJI. The reader can use this book as a solid platform for comparing their own approach to PJI treatment with the specialists’ recommendations.  

About the authors

Univ. Prof. Dr. Klaus-Dieter Kühn, Senior Scientific Advisor, Heraeus Medical GmbH, Wehrheim im Taunus

Table of contents (9 chapters)

Buy this book

eBook $84.99
price for USA (gross)
  • ISBN 978-3-662-54469-3
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $109.00
price for USA
  • Customers within the U.S. and Canada please contact Customer Service at 1-800-777-4643, Latin America please contact us at +1-212-460-1500 (Weekdays 8:30am – 5:30pm ET) to place your order.
  • Due: December 21, 2017
  • ISBN 978-3-662-54468-6
  • Free shipping for individuals worldwide
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Bibliographic Information

Bibliographic Information
Book Title
Management of Periprosthetic Joint Infection
Book Subtitle
A global perspective on diagnosis, treatment options, prevention strategies and their economic impact
Editors
  • Klaus-Dieter Kühn
Copyright
2018
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag GmbH Germany
eBook ISBN
978-3-662-54469-3
DOI
10.1007/978-3-662-54469-3
Hardcover ISBN
978-3-662-54468-6
Edition Number
1
Number of Pages
XVIII, 366
Number of Illustrations and Tables
196 illustrations in colour
Topics