Overview
- Editors:
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Michael Baumann
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Department of Radiation Oncology, University of Technology, Dresden, Germany
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Mechthild Krause
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Klinik und Poliklinik für Stra, Medizinische Fakultät und Univ, Dresden, Germany
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Nils Cordes
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University of Technology, Dresden, Germany
- Reviews our current understanding of the most important aspects of molecular radiobiology
- Discusses recent efforts to identify reasonable and clinically applicable biomarkers
- Describes how molecular information is being exploited for diagnostic imaging and imaging throughout treatment
- Includes supplementary material: sn.pub/extras
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Table of contents (10 chapters)
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- Kerstin Borgmann, Sabrina Köcher, Malte Kriegs, Wael Yassin Mansour, Ann Christin Parplys, Thorsten Rieckmann et al.
Pages 1-24
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- Wendy A. Woodward, Richard P. Hill
Pages 25-44
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- Shyhmin Huang, H. Peter Rodemann, Paul M. Harari
Pages 45-87
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- Anne Vehlow, Katja Storch, Daniela Matzke, Nils Cordes
Pages 89-106
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- Geoff S Higgins, Mechthild Krause, W Gillies McKenna, Michael Baumann
Pages 107-122
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- Dirk Vordermark, Michael R. Horsman
Pages 123-142
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- Jesper Grau Eriksen, Pernille Lassen
Pages 143-161
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- Dirk De Ruysscher, Karin Haustermans, Daniela Thorwarth
Pages 163-173
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- Robert Haase, Michael Andreeff, Nasreddin Abolmaali
Pages 175-187
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- Sebastian Zschaeck, Jörg Steinbach, Esther G.C. Troost
Pages 189-201
About this book
This book concisely reviews our current understanding of hypoxia, molecular targeting, DNA repair, cancer stem cells, and tumor pathophysiology, while also discussing novel strategies for putting these findings into practice in daily clinical routine. Radiotherapy is an important part of modern multimodal cancer treatment, and the past several years have witnessed not only substantial improvements in radiation techniques and the use of new beam qualities, but also major strides in our understanding of molecular tumor biology and tumor radiation response. Against this backdrop, the book highlights recent efforts to identify reasonable and clinically applicable biomarkers using broad-spectrum tissue microarrays and high-throughput systems biology approaches like genomics and epigenomics. In particular, it describes in detail how such molecular information is now being exploited for diagnostic imaging and imaging throughout treatment using the example of positron emission tomography.By discussing all these issues in the context of modern radiation oncology, the book provides a broad, up-to-date overview of the molecular aspects of radiation oncology that will hopefully foster its further optimization.
Editors and Affiliations
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Department of Radiation Oncology, University of Technology, Dresden, Germany
Michael Baumann
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Klinik und Poliklinik für Stra, Medizinische Fakultät und Univ, Dresden, Germany
Mechthild Krause
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University of Technology, Dresden, Germany
Nils Cordes
About the editors
Michael Baumann, University of Technology, Dresden, Germany.
Mechthild Krause, University of Technology, Dresden, Germany.
Nils Cordes, University of Technology, Dresden, Germany.
