Medication-Related Osteonecrosis of the Jaws

Bisphosphonates, Denosumab, and New Agents

Editors: Otto, Sven (Ed.)

  • Coverage of all aspects of osteonecrosis of the jaw related to treatment with antiresorptive drugs especially bisphosphonates and denosumab
  • Practical guidelines for students and practitioners
  • First standard textbook to be devoted to this hot topic
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eBook $119.00
price for USA (gross)
  • ISBN 978-3-662-43733-9
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $159.00
price for USA
  • ISBN 978-3-662-43732-2
  • Free shipping for individuals worldwide
  • Online orders shipping within 2-3 days.
Softcover $159.00
price for USA
  • ISBN 978-3-662-52433-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Osteonecrosis of the jaws is a well-known side-effect of antiresorptive therapy that predominantly occurs in patients suffering from malignant diseases and receiving intravenous administrations of nitrogen-containing bisphosphonates or subcutaneous administrations of denosumab, a monoclonal antibody. Less frequently it may also be observed in patients with osteoporosis who are being treated with these antiresorptive drugs 

This textbook provides detailed, up-to-date information on all aspects of medication-related osteonecrosis of the jaws, including clinical features, pathogenesis, treatment options, and preventive measures. It also explains safe prevention and treatment strategies for patients receiving antiresorptive drugs who require extractions, implant insertions, and other dento-alveolar surgeries. This book will be of major interest for medical and dental students, dentists, and oral and maxillofacial surgeons as well as osteologists and oncologists.

About the authors

Sven Otto, MD, DDS, is a board-certified specialist in oral and maxillofacial surgery from Germany. He received both his dental degree (2002) and his medical degree (2006) from the University of Leipzig, Germany. Since 2006 he has been a resident at the Department of Oral and Maxillofacial Surgery, Ludwig-Maximilians University of Munich, Germany. One of his major fields of interest is bisphosphonate-related osteonecrosis of the jaw, especially the underlying pathophysiology. He has published numerous articles in leading scientific journals and has lectured nationally and internationally on this subject. In 2011, he was appointed group leader for “Jaw bone and osteonecrosis of the jaw” in the Laboratory for Experimental Surgery and Regenerative Medicine (ExperiMed) of the Ludwig-Maximilians University of Munich.

Reviews

“… eine ideale Grundlage für jeden Zahnarzt und Oralchirurgen, um sich über das Krankheitsbild der Kiefernekrose unter antiresorptiven Medikamenten wie Bisphosphonaten und Denosumab zu informieren und sein Wissen bezüglich der zahnärztlichen Behandlung dieser Patienten zu erweitern. ... übersichtlich strukturierte und sehr gut illustrierte Kapitel ... in englischer Sprache erschienen, jedoch auch für Nicht-Muttersprachler sehr verständlich ... Insgesamt kann dieses Buch zahnärztlichen, oralchirurgischen und mund-, kiefer- und gesichtschirurgischen Kollegen nur empfohlen werden.” (Dr. Kleopatra Ziata, in: Bayerisches Zahnärzteblatt BZB, März 2015)


Table of contents (20 chapters)

  • Pharmacological Aspects of Antiresorptive Drugs: Bisphosphonates and Denosumab

    Bartl, Reiner (et al.)

    Pages 1-15

  • Bisphosphonate and Denosumab Therapy: Fields of Application

    Then, Cornelia (et al.)

    Pages 17-26

  • Risk Factors for Medication-Related Osteonecrosis of the Jaw

    Kwon, Tae-Geon

    Pages 27-42

  • Definition, Clinical Features and Staging of Medication-Related Osteonecrosis of the Jaw

    Otto, Sven (et al.)

    Pages 43-54

  • Epidemiology of Medication-Related Osteonecrosis of the Jaw

    Lazarovici, Towy Sorel (et al.)

    Pages 55-61

Buy this book

eBook $119.00
price for USA (gross)
  • ISBN 978-3-662-43733-9
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $159.00
price for USA
  • ISBN 978-3-662-43732-2
  • Free shipping for individuals worldwide
  • Online orders shipping within 2-3 days.
Softcover $159.00
price for USA
  • ISBN 978-3-662-52433-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Medication-Related Osteonecrosis of the Jaws
Book Subtitle
Bisphosphonates, Denosumab, and New Agents
Editors
  • Sven Otto
Copyright
2015
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-662-43733-9
DOI
10.1007/978-3-662-43733-9
Hardcover ISBN
978-3-662-43732-2
Softcover ISBN
978-3-662-52433-6
Edition Number
1
Number of Pages
VIII, 220
Number of Illustrations and Tables
20 b/w illustrations, 63 illustrations in colour
Topics