Current Topics in Microbiology and Immunology

Interleukin-10 in Health and Disease

Editors: Fillatreau, Simon, O'Garra, Anne (Eds.)

  • Presents an in-depth and global analysis of how IL-10 contributes to immunity
  • Offers a set of reviews dedicated to the biology of IL-10
  • Provides a comprehensive overview on one of the most important anti-inflammatory cytokines
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eBook $149.00
price for USA (gross)
  • ISBN 978-3-662-43492-5
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
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  • Immediate eBook download after purchase
Hardcover $189.00
price for USA
  • ISBN 978-3-662-43491-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $189.00
price for USA
  • ISBN 978-3-662-52405-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This volume provides a set of reviews dedicated to the biology of Interleukin (IL)-10. It includes chapters on its importance for maintaining immune homeostasis in humans, its role in intestinal immunity and its functions during viral and bacterial infections. In addition, it presents reviews on the mechanisms linking innate microbial recognition to the production of IL-10 and on how IL-10 recognition by its receptor functions. The roles of T and B cells as relevant sources of IL-10 are also discussed, with an emphasis on the clinical opportunities offered by IL-10-producing Tr1 cells for the suppression of unwanted immunity. Finally, the functions of other cytokines of the IL-10 family are presented. Collectively, these articles provide a comprehensive overview of our current knowledge on one of the most important anti-inflammatory cytokines known to date.

Table of contents (10 chapters)

  • IL-10 in Humans: Lessons from the Gut, IL-10/IL-10 Receptor Deficiencies, and IL-10 Polymorphisms

    Engelhardt, Karin R. (et al.)

    Pages 1-18

  • Control of Intestinal Inflammation by Interleukin-10

    Kole, Abhisake (et al.)

    Pages 19-38

  • Tr1 Cells and the Counter-Regulation of Immunity: Natural Mechanisms and Therapeutic Applications

    Roncarolo, Maria Grazia (et al.)

    Pages 39-68

  • Interleukin-10-Producing B Cells and the Regulation of Immunity

    Hilgenberg, Ellen (et al.)

    Pages 69-92

  • Pathogen Manipulation of cIL-10 Signaling Pathways: Opportunities for Vaccine Development?

    Eberhardt, Meghan K. (et al.)

    Pages 93-128

Buy this book

eBook $149.00
price for USA (gross)
  • ISBN 978-3-662-43492-5
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $189.00
price for USA
  • ISBN 978-3-662-43491-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $189.00
price for USA
  • ISBN 978-3-662-52405-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Interleukin-10 in Health and Disease
Editors
  • Simon Fillatreau
  • Anne O'Garra
Series Title
Current Topics in Microbiology and Immunology
Series Volume
380
Copyright
2014
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-662-43492-5
DOI
10.1007/978-3-662-43492-5
Hardcover ISBN
978-3-662-43491-8
Softcover ISBN
978-3-662-52405-3
Series ISSN
0070-217X
Edition Number
1
Number of Pages
VIII, 238
Number of Illustrations and Tables
16 illustrations in colour
Topics