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  • © 1996

Intracellular Signal Transduction: The JAK-STAT Pathway

Part of the book series: Molecular Biology Intelligence Unit (MBIU)

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Table of contents (9 chapters)

  1. Front Matter

    Pages i-vii
  2. Intracellular Signal Transduction

    • Andrew F. Wilks, Ailsa G. Harpur
    Pages 1-22
  3. The Cytokine Receptor Family

    • Andrew F. Wilks, Ailsa G. Harpur
    Pages 23-43
  4. The JAK Family of Protein Tyrosine Kinases

    • Andrew F. Wilks, Ailsa G. Harpur
    Pages 45-61
  5. Signal Transducers and Activators of Transcription: The STAT Proteins

    • Andrew F. Wilks, Ailsa G. Harpur
    Pages 63-77
  6. STFs: STAT-Containing Transcription Factors

    • Andrew F. Wilks, Ailsa G. Harpur
    Pages 79-91
  7. A Guided Tour Through The JAK-STAT Pathway

    • Andrew F. Wilks, Ailsa G. Harpur
    Pages 105-132
  8. Future Trends

    • Andrew F. Wilks, Ailsa G. Harpur
    Pages 153-167
  9. Back Matter

    Pages 169-209

About this book

This book is the first one written about the JAK/STAT pathway. The JAK (Janus Kinase) Protein tyrosine kinases are novel phosphotransferases absolutely required for cellular signalling downstream of non-catalytic cytokine receptors (amongst others). These molecules are components in pathways utilising the STAT (Signal Transducers and Activators of Transcription) transcription factors. The basic components of the JAK/STAT pathway are covered in detail, and the centre piece of the book is a guided tour of the pathway itself. An interesting addition to the book is the chapter on the use of Drosophila melanogaster as a genetic system to probe the pathway at the whole organism level. The book is targeted to researchers who have an interest in intracellular signalling.

Authors and Affiliations

  • Ludwig Institute for Cancer Research, Melbourne, Australia

    Andrew F. Wilks, Ailsa G. Harpur

Bibliographic Information

  • Book Title: Intracellular Signal Transduction: The JAK-STAT Pathway

  • Authors: Andrew F. Wilks, Ailsa G. Harpur

  • Series Title: Molecular Biology Intelligence Unit

  • DOI: https://doi.org/10.1007/978-3-662-22050-4

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1996

  • Softcover ISBN: 978-3-662-22052-8Published: 13 November 2013

  • eBook ISBN: 978-3-662-22050-4Published: 29 June 2013

  • Series ISSN: 1431-0414

  • Edition Number: 1

  • Number of Pages: VII, 209

  • Number of Illustrations: 30 b/w illustrations

  • Additional Information: Jointly published with R.G. Landes, Biomedical Publishers, Austin, USA

  • Topics: Cell Biology, Biochemistry, general, Cancer Research

Buy it now

Buying options

eBook USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access