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Intracellular Signal Transduction: The JAK-STAT Pathway

  • Book
  • © 1996

Overview

Authors:
  1. Andrew F. Wilks

    1. Ludwig Institute for Cancer Research, Melbourne, Australia

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    You can also search for this author in PubMed   Google Scholar

  2. Ailsa G. Harpur

    1. Ludwig Institute for Cancer Research, Melbourne, Australia

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    You can also search for this author in PubMed   Google Scholar

Part of the book series: Molecular Biology Intelligence Unit (MBIU)

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Table of contents (9 chapters)

  1. Front Matter

    Pages i-vii
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  2. Intracellular Signal Transduction

    • Andrew F. Wilks, Ailsa G. Harpur
    Pages 1-22

  3. The Cytokine Receptor Family

    • Andrew F. Wilks, Ailsa G. Harpur
    Pages 23-43

  4. The JAK Family of Protein Tyrosine Kinases

    • Andrew F. Wilks, Ailsa G. Harpur
    Pages 45-61

  5. Signal Transducers and Activators of Transcription: The STAT Proteins

    • Andrew F. Wilks, Ailsa G. Harpur
    Pages 63-77

  6. STFs: STAT-Containing Transcription Factors

    • Andrew F. Wilks, Ailsa G. Harpur
    Pages 79-91

  7. Somatic Cell Genetic Dissection of Interferon Signal Transduction Pathways

    • Andrew F. Wilks, Ailsa G. Harpur
    Pages 93-103

  8. A Guided Tour Through The JAK-STAT Pathway

    • Andrew F. Wilks, Ailsa G. Harpur
    Pages 105-132

  9. Hopscotch/Tumorous Lethal: A JAK Family Member from Drosophila Melanogaster

    • Andrew F. Wilks, Ailsa G. Harpur
    Pages 133-152

  10. Future Trends

    • Andrew F. Wilks, Ailsa G. Harpur
    Pages 153-167

  11. Back Matter

    Pages 169-209
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Keywords

About this book

This book is the first one written about the JAK/STAT pathway. The JAK (Janus Kinase) Protein tyrosine kinases are novel phosphotransferases absolutely required for cellular signalling downstream of non-catalytic cytokine receptors (amongst others). These molecules are components in pathways utilising the STAT (Signal Transducers and Activators of Transcription) transcription factors. The basic components of the JAK/STAT pathway are covered in detail, and the centre piece of the book is a guided tour of the pathway itself. An interesting addition to the book is the chapter on the use of Drosophila melanogaster as a genetic system to probe the pathway at the whole organism level. The book is targeted to researchers who have an interest in intracellular signalling.

Authors and Affiliations

  • Ludwig Institute for Cancer Research, Melbourne, Australia

    Andrew F. Wilks, Ailsa G. Harpur

Bibliographic Information

  • Book Title: Intracellular Signal Transduction: The JAK-STAT Pathway

  • Authors: Andrew F. Wilks, Ailsa G. Harpur

  • Series Title: Molecular Biology Intelligence Unit

  • DOI: https://doi.org/10.1007/978-3-662-22050-4

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1996

  • Softcover ISBN: 978-3-662-22052-8Published: 13 November 2013

  • eBook ISBN: 978-3-662-22050-4Published: 29 June 2013

  • Series ISSN: 1431-0414

  • Edition Number: 1

  • Number of Pages: VII, 209

  • Number of Illustrations: 30 b/w illustrations

  • Additional Information: Jointly published with R.G. Landes, Biomedical Publishers, Austin, USA

  • Topics: Cell Biology, Biochemistry, general, Cancer Research

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