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Interleukin-10

  • Book
  • © 1995

Overview

Authors:
  1. Jan E. Vries

    1. Department of Human Immunology, DNAX Research Institute, Palo Alto, USA

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  2. René Waal Malefyt

    1. Department of Human Immunology, DNAX Research Institute, Palo Alto, USA

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    You can also search for this author in PubMed   Google Scholar

Part of the book series: Molecular Biology Intelligence Unit (MBIU)

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Table of contents (17 chapters)

  1. Front Matter

    Pages ii-xvi
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  2. Molecular Biology of Interleukin-10 and its Receptor

    • Kevin W. Moore, Alice S.-Y. Ho, Jiangchun Xu-Amano
    Pages 1-9

  3. Physicochemical and Structural Properties of Interleukin-10

    • Paul P. Trotta, William T. Windsor
    Pages 11-18

  4. IL-10 and Human T Cells

    • Hans Yssel, René de Waal Malefyt
    Pages 19-27

  5. Interleukin-10 and B Lymphocytes

    • Francine Brière, Jacques Banchereau
    Pages 29-36

  6. Regulation of Human Monocyte Functions by Interleukin-10

    • René de Waal Malefyt, Carl G. Figdor, Jan E. de Vries
    Pages 37-52

  7. Interleukin-10: An Inhibitor of Macrophage-Dependent Stimulation of Th1 Cells

    • Anne O’Garra
    Pages 53-58

  8. IL-10 and Bone Formation/Hematopoiesis

    • Peter Van Vlasselaer
    Pages 59-67

  9. Regulatory Function of IL-10 in Experimental Parasitic Infections

    • Steven G. Reed, Alan Sher
    Pages 69-77

  10. IL-10 in Mycobacterial Infection

    • Peter A. Sieling, Robert L. Modlin
    Pages 79-89

  11. IL-10 In Human Leishmaniasis

    • Edgar M. Carvalho
    Pages 91-100

  12. IL-10 and HIV-1 Replication

    • Hanneke Schuitemaker, Neeltje A. Kootstra, Frank Miedema
    Pages 101-112

  13. Interleukin-10 and Transplantation Tolerance

    • Maria-Grazia Roncarolo
    Pages 113-120

  14. Effects of IL-10 in Lipopolysaccharide- and Superantigen-Induced Lethal Shock In Vivo

    • Albert Zlotnik, Rachel A. Freiberg
    Pages 121-126

  15. Inhibition of Cell-Mediated Immune Responses In Vivo by Recombinant IL-10

    • Fiona Powrie, Robert L. Coffman
    Pages 127-133

  16. IL-10 Transgenic Mice

    • Myung-Shik Lee, Nora Sarvetnick
    Pages 135-139

  17. Interleukin-10 Deficient Mice

    • Donna Rennick, Dan Berg, Ralf Kühn, Werner Müller
    Pages 141-148

  18. A Phase I Study of Interleukin-10 in Healthy Humans: Safety and Effects on Cytokine Production

    • Amy E. Chernoff, Eric V. Granowitz, Leland Shapiro, Edouard Vannier, Gerhard Lonnemann, Jonathan B. Angel et al.
    Pages 149-158

  19. Back Matter

    Pages 159-167
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Keywords

About this book

The presented information reflects a state-of-the-art summary of the pleiotropic effects of IL-10 in vitro and in vivo and will contribute to our understanding of the role of ILj-10 in the immune system and its potential clinicial utility in the near future. The book contains chapters in which the in vitro biological effects of IL-10 on both mouse and human lymphoid and myeloid cells are reviewed. In addition, the role of IL-10 in transplantation, parasite infections, inflammation, infectious diseases and bone formation is described. The effects of IL-10 in vivo are presented, describing an IL-10 transgenic mouse model, the IL-10 "knock-out" mouse, and the capacity of IL-10 to prevent lethal toxic shock in mice.

Authors and Affiliations

  • Department of Human Immunology, DNAX Research Institute, Palo Alto, USA

    Jan E. Vries, René Waal Malefyt

Bibliographic Information

  • Book Title: Interleukin-10

  • Authors: Jan E. Vries, René Waal Malefyt

  • Series Title: Molecular Biology Intelligence Unit

  • DOI: https://doi.org/10.1007/978-3-662-22038-2

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1995

  • Softcover ISBN: 978-3-662-22040-5Published: 03 October 2013

  • eBook ISBN: 978-3-662-22038-2Published: 29 June 2013

  • Series ISSN: 1431-0414

  • Edition Number: 1

  • Number of Pages: XII, 165

  • Number of Illustrations: 25 b/w illustrations, 2 illustrations in colour

  • Additional Information: Jointly published with R.G. Landes, Biomedical Publishers, Austin, USA

  • Topics: Cell Biology

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