Ernst Schering Foundation Symposium Proceedings

Gene Therapy

Editors: Sobol, Robert E., Scanlon, Kevin J., Nestaas, Eirik (Eds.)

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About this book

This book is a collection of preclinical and clinical reports on the application of gene therapy to human disease. The two methods available for delivering therapeutic genes to diseased cells, viral and non-viral vector systems, are detailed and characterized. Several reports describe both approaches currently used in gene therapy: the introduction of a wild-type gene to restore normal gene function in diseased cells, and the use of antisense molecules to hinder abnormal gene expression. Clinical studies detail several different strategies for the treatment of cancer and cardiovascular diseases, using genetic material as therapeutic agents. The regulatory issues governing the use of gene therapy in Europe and the United States are also presented. This book highlights the range of applications and demonstrates the rapid progress being made in the field of gene therapy.

Table of contents (12 chapters)

  • Human Gene Therapy: Future Prospects

    Gottesman, M. M.

    Pages 1-16

  • Approaches to the Gene Therapy of Cancer Using Replication-Competent Oncolytic Adenoviruses

    Heise, C. (et al.)

    Pages 17-25

  • Discovery, Development, and Application of Synthetic Gene Delivery Systems

    Felgner, P. L.

    Pages 27-50

  • Tumor Suppressor Genes

    Weissman, B. E.

    Pages 51-76

  • Oligonucleotide Therapeutics for Human Leukemia

    Gewirtz, A. M.

    Pages 77-95

Buy this book

eBook $74.99
price for USA (gross)
  • ISBN 978-3-662-03577-1
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $99.00
price for USA
  • ISBN 978-3-662-03579-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Gene Therapy
Editors
  • Robert E. Sobol
  • Kevin J. Scanlon
  • Eirik Nestaas
Series Title
Ernst Schering Foundation Symposium Proceedings
Series Volume
27
Copyright
1998
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-662-03577-1
DOI
10.1007/978-3-662-03577-1
Softcover ISBN
978-3-662-03579-5
Series ISSN
0947-6075
Edition Number
1
Number of Pages
XII, 242
Number of Illustrations and Tables
25 b/w illustrations
Topics