Frontiers of Virology

Pathogenicity of Human Herpesviruses due to Specific Pathogenicity Genes

Editors: Becker, Yechiel, Darai, Gholamreza (Eds.)

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About this book

Six members of the Herpesviridae family are human pathogens, including herpes and 2 (HSV-I and 2), Epstein-Barr virus (EBV), varicella zoster simplex virus I virus (VZV), human cytomegalovirus (HCMV), and human herpesvirus 6 (HHV 6). Each of these viruses is capable of causing distinct diseases of varying severity in children, young adults, and the aged. The diseases range from infection of epithelial tissue to the infection of internal organs and white blood cells. A common feature of the six pathogenic human herpesviruses is their ability to latently infect different cell types in which the viral DNA is not integrated and is unable to express its pathogenicity. Reactivation of the herpesviruses is a result of cellular processes which reactivate viral genes, leading to virus progeny and to signs of infection. Due to their ability to become latent after initial infection, once the pathogenic herpesviruses infect children they are maintained throughout life, having the potential of cause various diseases upon reactivation.

Table of contents (22 chapters)

  • Entry of Herpes Simplex Virus Type 1 into Cells — Early Steps in Virus Pathogenicity

    Becker, Yechiel (et al.)

    Pages 3-20

  • Neomycin and Herpes Simplex Virus Receptor Binding: The Role of Glycoprotein C

    Øyan, Anne M. (et al.)

    Pages 21-32

  • Pathogenicity of Glycoprotein C-Negative Herpes Simplex Virus Type 1 in Herpetic Keratitis

    Toh, Yasushi (et al.)

    Pages 33-42

  • Structure and Function of Glycoprotein D of Herpes Simplex Virus

    Eisenberg, R. J. (et al.)

    Pages 43-65

  • The Role of Herpes Simplex Virus Thymidine Kinase Expression in Pathogenesis and Latency

    Tenser, Richard B.

    Pages 68-86

Buy this book

eBook $109.00
price for USA (gross)
  • ISBN 978-3-642-85004-2
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $149.00
price for USA
  • ISBN 978-3-642-85006-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Pathogenicity of Human Herpesviruses due to Specific Pathogenicity Genes
Editors
  • Yechiel Becker
  • Gholamreza Darai
Series Title
Frontiers of Virology
Series Volume
3
Copyright
1994
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-85004-2
DOI
10.1007/978-3-642-85004-2
Softcover ISBN
978-3-642-85006-6
Series ISSN
1431-357X
Edition Number
1
Number of Pages
XVI, 387
Topics