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Diagnosis of Human Viruses by Polymerase Chain Reaction Technology

  • Book
  • © 1992

Overview

Editors:
  1. Yechiel Becker

    1. Department of Molecular Virology Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel

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    You can also search for this editor in PubMed   Google Scholar

  2. Gholamreza Darai

    1. Institut für Medizinische Virologie, der Universität Heidelberg, Heidelberg, Germany

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Frontiers of Virology (FRVIROLOGY, volume 1)

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Table of contents (30 chapters)

  1. Front Matter

    Pages I-XVII
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  3. Human Hepatitis Viruses

    1. Front Matter

      Pages 55-55
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    2. Antigen Capture/Polymerase Chain Reaction for the Detection of Hepatitis A Virus in Human Clinical Materials

      • Robert W. Jansen, Stanley M. Lemon
      Pages 57-66

    3. Clinical Diagnosis of Hepatitis B Infection: Applications of the Polymerase Chain Reaction

      • Geoffrey Dusheiko, Jianye Xu, Arie J. Zuckermann
      Pages 67-85

    4. Application of Polymerase Chain Reaction to Hepatitis C Virus Research and Diagnostics

      • Amy J. Weiner, Venkatakrishna Shyamala, J. Eric Hall, Michael Houghton, Jang Han
      Pages 86-100

    5. Polymerase Chain Reaction for Hepatitis Delta Virus RNA Identification and Characterization

      • Anna Linda Zignego, Paul Deny, Paolo Gentilini, Christian Brechot
      Pages 101-116

  4. Human Herpes Viruses

    1. Front Matter

      Pages 117-117
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    2. Polymerase Chain Reaction Detection of Herpes Simplex Virus in Cerebrospinal Fluid

      • R. H. Boerman, A. C. B. Peters, E. P. J. Arnoldus, A. K. Raap, A. M. van Loon, B. R. Bloem et al.
      Pages 119-133

    3. Polymerase Chain Reaction Diagnosis of Varicella Zoster Virus

      • Ravi Mahalingam, Randall Cohrs, Aud N. Dueland, Donald H. Gilden
      Pages 134-146

    4. Detection of Human Cytomegalovirus by Polymerase Chain Reaction

      • Mark F. Mangano, Richard L. Hodinka, Jordan G. Spivack
      Pages 147-156

    5. Semiquantitative Analysis of Epstein-Barr Virus DNA by Polymerase Chain Reaction in Clinical Samples of Lymphoproliferative Disorders

      • Hans Knecht, Roland Sahli, David J. L. Joske, Edith Bachmann, Fedor Bachmann, Daniel Hayoz et al.
      Pages 157-170

    6. Detection of Human Herpesvirus 6 DNA in Clinical Samples of Patients by Polymerase Chain Reaction Amplification

      • K. Kondo, C. Tomomori, T. Kondo, T. Mukai, T. Yamamoto, K. Yamanishi
      Pages 171-181

  5. Human Papova Viruses

    1. Front Matter

      Pages 183-183
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    2. Human Papillomavirus Infections of the Genital Tract: Clinical Significance and Diagnosis by Polymerase Chain Reaction

      • Stina Syrjänen, Kari Syrjänen
      Pages 185-207
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Keywords

About this book

The basis for the effective treatment and cure of a patient is the rapid diagnosis of the disease and its causative agent, which is based on the analysis of the clinical symptoms coupled with laboratory tests. Although rapid advance­ ments have been made in the laboratory diagnosis of virus diseases, the neces­ sary isolation of the causative virus from the clinical specimens is a relatively long procedure. Viruses which integrate into the cellular DNA (such as human immunodeficiency virus, HIV -1, or hepatitis B virus) are difficult to identify by molecular techniques, while viruses which exist in the clinical material in low concentrations are even more formidable to identify. Recently, the application of the polymerase chain reaction (peR) technique developed by K. D. Mullis and detailed in the study by Saiki et al. (1985) led to a revolution in virus diagnosis. The peR technique was rapidly applied to the diagnosis of viruses in clinical material. Volume 1 of Frontiers of Virology provides new information on the advan­ tages of the use of the peR for the diagnosis of many human disease-causing viruses, as well as on some problems with its use.

Editors and Affiliations

  • Department of Molecular Virology Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel

    Yechiel Becker

  • Institut für Medizinische Virologie, der Universität Heidelberg, Heidelberg, Germany

    Gholamreza Darai

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