Intraoperative Radiotherapy

1. Front Matter

   Pages I-XII

   PDF

2. Intraoperative Radiotherapy: Rationale and Program Development

   • Felipe A. Calvo, Manuel Santos, Luther W. Brady

   Pages 1-9

3. Physics

   • Lluis Escudé, David Ortiz de Urbina, Enrico Tangco

   Pages 11-23

4. Anesthesia and Hospital Coordination

   • David Ortiz de Urbina, Enrico Tangco, José Luis Arroyo, Francisco Carrascosa

   Pages 25-30

5. Intracranial Tumors

   • Felipe A. Calvo, Oscar Abuchaibe, Vicente Vanaclocha, Francisco Aguilera

   Pages 31-36

6. Head and Neck Cancer

   • Felipe A. Calvo, Oscar Abuchaibe, José María Serra, Rafael García-Tapia

   Pages 37-41

7. Lung Cancer

   • Felipe A. Calvo, David Ortiz de Urbina, Jesús Herreros, Rafael Llorens

   Pages 43-50

8. Gastric Cancer

   • Felipe A. Calvo, Manuel Santos, Fernando Pardo, José L. Hernández, Javier Alvarez-Cienfuegos, Juan Voltas

   Pages 51-56

9. Pancreatic Cancer

   • Felipe A. Calvo, Ignacio Azinovic, Gerardo Zornoza, Juan Voltas, Fernando Pardo, Javier Alvarez-Cienfuegos

   Pages 57-64

10. Colorectal Cancer

    • Felipe A. Calvo, Ignacio Azinovic, Fernando Pardo, José L. Hernández, Javier Alvarez-Cienfuegos

    Pages 65-72

11. Bladder Cancer

    • Felipe A. Calvo, Oscar Abuchaibe, Javier Aristu, Javier Zudiare, José María Berián

    Pages 73-78

12. Gynecologic Cancer

    • Felipe A. Calvo, David Ortiz de Urbina, Fernando de la Fuente, Matias Jurado, José María Berián

    Pages 79-84

13. Retroperitoneal and Other Central Soft Tissue Sarcomas

    • Felipe A. Calvo, Oscar Abuchaibe, José María Serra, José María Berián, José Cañadell

    Pages 85-90

14. Soft Tissue Sarcomas of the Extremities

    • Felipe A. Calvo, David Ortiz de Urbina, José L. Beguiristain, Santiago Amillo, Josá Cañadell

    Pages 91-97

15. Ewing’s Sarcoma

    • Felipe A. Calvo, Oscar Abuchaibe, Carlos Villas, José Cañadell, Luis Sierrasesúmaga

    Pages 99-102

16. Osteosarcoma

    • Felipe A. Calvo, Ignacio Azinovic, Santiago Amillo, José Cañadell, Luis Sierrasesúmaga

    Pages 103-108

17. Summary and Future Prospects

    • Felipe A. Calvo, Manuel Santos, Luther W. Brady

    Pages 109-114

18. Back Matter

    Pages 115-120

    PDF

The development of the capacity to use electron beams at various energies stimulated the development of the new technology of intraoperative radiation therapy. The visual­ ization of the primary tumor, definition of the site to be irradiated, and knowledge of the size of tumor to be irradiated, including adequate margins for microscopic extent along with debulking of the tumor, have allowed intraoperative radiation therapy to be pur­ sued in a wide variety of disease processes. Not only is it possible to treat tumors that were highly resistant, but it is also possible to specifically localize the tumor with a mar­ gin adequate to encompass potential microscopic extensions and to choose the appro­ priate electron beam energy to treat the potential residual tumor and spare the adjacent normal structures. It is, furthermore, possible to treat patients with unresectable tumors. Central to this entire development is the fact that normal structures can be removed from the field of treatment. In the beginning, the emphasis was on single fractions of electron beam radiation without subsequent supplementation by external photon beam radiation therapy. How­ ever, more recently it has become necessary to use not only a single electron beam frac­ tion during the course of the operation, but to supplement it with external beam treat­ ment. The encouraging results obtained with intraoperative radiation therapy have led to clinical trials at a large number of institutions throughout the world.

• Chirurgie
• Intraoperative Strahlentherapie
• Onkologie
• Radiologie
• Strahlentherapie
• Surgery
• Tumor
• cancer
• gastric cancer
• histology
• oncology
• pancreatic cancer
• radiation
• radiology
• radiotherapy
• Radiaton Oncology

• Department of Radiation Oncology, Hahnemann University, Philadelphia, USA

  Luther W. Brady

• Department of Oncology, Clinica Universitaria, Pamplona, Spain

  Manual Santos

Policies and ethics