Buy this book

eBook $74.99
price for USA (gross)
  • ISBN 978-3-642-82792-1
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $99.00
price for USA
  • ISBN 978-3-642-82794-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

In 1965 I was asked by Dr. Konrad Springer whether I would consider writing a monograph on "Lampbrush chromosomes and their physiological meaning", and although I accepted in principle I refused to write there and then, or to meet a deadline. I wanted to continue with my own research, and I had other responsibilities that left me with little free time, but a much more important consideration was that in the 1960s the subject was beset by a host of unresolved questions. I felt that to write a review then would be premature, full of speculations many of which would be refuted, and indeed were refuted, within the next decade or two. Had I written at that time the only real advantage over the present would have been that few biologists were studying lampbrush chromo­ somes, and the published literature was therefore scanty. I am glad that I insisted on delay, and am grateful for Springer Verlag's patient acceptance of my decision. The first chapter of this monograph describes the history of research on lampbrush chromosomes from their discovery towards the end of the 19th century until the early 1960s. By then several facts concerning their structure and chemistry had been firmly established, including the evidence that a lampbrush chromatid is unineme; it contains a single uninterrupted DNA duplex. This exposed a major problem, the C-value paradox; grades of complexity of organization in eukaryotes are unrelated to their genome sizes.

Table of contents (9 chapters)

  • Historical Introduction

    Callan, Harold Garnet

    Pages 1-24

  • Techniques for the Study of Lampbrush Chromosomes

    Callan, Harold Garnet

    Pages 25-49

  • Chromosome Identification

    Callan, Harold Garnet

    Pages 50-105

  • Morphological Aspects of RNA Transcription on Lampbrush Chromosomes

    Callan, Harold Garnet

    Pages 106-132

  • Distribution of Nucleic Acid Sequences in Lampbrush Chromosomes

    Callan, Harold Garnet

    Pages 133-164

Buy this book

eBook $74.99
price for USA (gross)
  • ISBN 978-3-642-82792-1
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $99.00
price for USA
  • ISBN 978-3-642-82794-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Loading...

Recommended for you

Loading...

Bibliographic Information

Bibliographic Information
Book Title
Lampbrush Chromosomes
Authors
Series Title
Molecular Biology, Biochemistry and Biophysics Molekularbiologie, Biochemie und Biophysik
Series Volume
36
Copyright
1986
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-82792-1
DOI
10.1007/978-3-642-82792-1
Softcover ISBN
978-3-642-82794-5
Series ISSN
0077-0221
Edition Number
1
Number of Pages
IX, 256
Number of Illustrations and Tables
182 b/w illustrations
Topics