Nato ASI Subseries H:

Ataxia-Telangiectasia

Editors: Gatti, Richard A., Painter, Robert B. (Eds.)

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eBook $74.99
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  • ISBN 978-3-642-78278-7
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Softcover $99.00
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About this book

Ataxia-telangiectasia or A-T is a fatal progressive neurological disease of children. The symptoms indicate disruptions in the development of such diverse body parts as cerebellum, thymus and chromosomes. The patients are unduly sensitive to ionizing radiation, immunodeficient, and a third of them develops cancer. All of this stems from defects of a single gene. Provided here is an up-to-date review of all important work in thefield. A wide spectrum of topics is covered, namely genetics, chromosome 11 mapping, radiobiology, complementation, heterozygote identification, clinical variants, biochemistry, and treatment of A-T.

Table of contents (23 chapters)

  • Ataxia-Telangiectasia: A Brief Historical Overview

    Sedgwick, Robert P.

    Pages 1-3

  • Cloning and Characterization of a Candidate Gene for A-T Complementation Group D

    Kapp, Leon N. (et al.)

    Pages 7-22

  • Precise Localization of a Gene Responsible for Ataxia-Telangiectasia on Chromosome 11q

    Cornélis, F. (et al.)

    Pages 23-35

  • How Many Ataxia-Telangiectasia Genes?

    Lange, Ethan (et al.)

    Pages 37-54

  • Isolation of Human cDNAS That Complement the Ataxia-Telangiectasia Phenotype in Cultured Fibroblasts

    Meyn, M. Stephen (et al.)

    Pages 55-64

Buy this book

eBook $74.99
price for USA (gross)
  • ISBN 978-3-642-78278-7
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $99.00
price for USA
  • ISBN 978-3-642-78280-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Ataxia-Telangiectasia
Editors
  • Richard A. Gatti
  • Robert B. Painter
Series Title
Nato ASI Subseries H:
Series Volume
77
Copyright
1993
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-78278-7
DOI
10.1007/978-3-642-78278-7
Softcover ISBN
978-3-642-78280-0
Series ISSN
1010-8793
Edition Number
1
Number of Pages
XXIII, 283
Number of Illustrations and Tables
18 b/w illustrations
Topics