Current Topics in Microbiology and Immunology

Herpes Simplex Virus

Pathogenesis, Immunobiology and Control

Editors: Rouse, Barry T. (Ed.)

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About this book

Although upstaged by the tragic appearance of the human immunodeficiency virus, herpes simplex viruses (HSV) types 1 and 2 continue to be major human pathogens against which we lack acceptable vaccines or other means of immunological control. The virus is large and complex, coding for 70 or more proteins. Although many mysteries remain to be unraveled, our knowledge base regarding genomic organization, gene expression and regulation, pathogenesis, and immune recog­ nition of component parts is quite considerable. Indeed, meet­ ings devoted entirely to herpesviruses are conspicuous by their frequency and excellent, yet sometimes exclusive, attendance. The purpose of this volume is to compile in a single book a series of reviews by leading investigators that deal with various aspects of virus-host interactions and which hopefully will pro­ vide clues as to how to best manage HSV from an immunobio­ logical perspective. Ultimately, one anticipates that a full under­ standing of virus-host interaction will lead to strategies useful for the prevention and control of HSV. The state of current progress with conventional vaccines is presented, as is a chapter on intracellular immunization. This latter novel approach to virus infections comes at approximately the bicentenary of Jenner's introduction of a successful conventional immunization strategy.

Table of contents (10 chapters)

  • Regulation of Herpes Simplex Virus Type 1 Gene Expression

    Hay, J. (et al.)

    Pages 1-14

  • Pathogenesis of Herpes Simplex Virus Infection and Animal Models for Its Study

    Stanberry, L. R.

    Pages 15-30

  • The Role of Immune Mechanisms in Control of Herpes Simplex Virus Infection of the Peripheral Nervous System

    Simmons, A. (et al.)

    Pages 31-56

  • The Role of T Cell Immunity in Control of Herpes Simplex Virus

    Schmid, D. S. (et al.)

    Pages 57-74

  • The Role of Antibody in Herpes Simplex Virus Infection in Humans

    Kohl, S.

    Pages 75-88

Buy this book

eBook $109.00
price for USA (gross)
valid through November 5, 2017
  • ISBN 978-3-642-77247-4
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $149.00
price for USA
valid through November 5, 2017
  • ISBN 978-3-642-77249-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Herpes Simplex Virus
Book Subtitle
Pathogenesis, Immunobiology and Control
Editors
  • Barry T. Rouse
Series Title
Current Topics in Microbiology and Immunology
Series Volume
179
Copyright
1992
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin, Heidelberg
eBook ISBN
978-3-642-77247-4
DOI
10.1007/978-3-642-77247-4
Softcover ISBN
978-3-642-77249-8
Series ISSN
0070-217X
Edition Number
1
Number of Pages
X, 179
Number of Illustrations and Tables
2 b/w illustrations
Topics