Pathophysiology and Pharmacology of Erythropoietin

Editors: Pagel, Horst, Weiss, Christoph, Jelkmann, Wolfgang (Eds.)

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About this book

I am honored to be invited to prepare a foreword for the proceedings of the Second International Lubeck Conference on Erythropoietin (Epo). I congratulate Wolfgang Jelkmann, Horst Pagel and Christoph Weiss for their organization of an excellent program for this conference which updated all of us on the advances made in erythropoietin research during the past few years since the first conference in June of 1988. I am sure that Professor Paul Carnot, had he been present at this conference, would be very pleased and proud of the advances made in the field of erythropoietin since his and Madame DeFlandre's seminal finding in 1906 (1) that rabbits produced a humoral substance following bleeding which controls red blood cell production. The reports by Hjort in 1936 (2) and by Erslev in 1953 (3) that large volumes of plasma or serum from rabbits following a bleeding stimulus, when injected into normal donor rabbits, produced a reticulocytosis, were very significant in confirming the existence of a humoral factor which controls erythropoiesis. Reissmann's parabiotic rat experiments in 1950 (4) reawakened interest in erythropoietin when he proved that hypoxia stimulated the production of a factor which regulates red cell produc­ tion. The studies of several investigators such as Jacobson et al. (5), Fisher and Birdwell (6), Kuratowska et al. (7) and Nathan et al.

Table of contents (2 chapter)

  • The Developmental Biology of Erythropoiesis and Erythropoietin: Is Erythropoietin a True Hormone or a Paracrine Factor?

    I. N. Rich, G. Noé

    Pages 79-87

    Buy Chapter $29.95
  • Clinical Applicability of the Determination of Erythropoietin

    M. Wolff, W. Jelkmann

    Pages 99-107

    Buy Chapter $29.95
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Buy this book

eBook $69.95 net
( price for USA )
  • ISBN 978-3-642-77074-6
  • digitally watermarked, no DRM
  • included format: PDF
  • eBooks can be used on all Reading Devices
Softcover $99.00 net
( price for USA )
  • ISBN 978-3-642-77076-0
  • free shipping for individuals worldwide
  • usually dispatched within 3 to 5 business days

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Bibliographic Information

Bibliographic Information
Book Title
Pathophysiology and Pharmacology of Erythropoietin
Copyright
1992
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-77074-6
DOI
10.1007/978-3-642-77074-6
Softcover ISBN
978-3-642-77076-0
Edition Number
1
Topics