Nato ASI Subseries H:

Host-Parasite Cellular and Molecular Interactions in Protozoal Infections

Editors: Chang, K.-P., Snary, David (Eds.)

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About this book

Tropical diseases such as leishmaniasis, malaria. trypanosomiasis, toxoplasmosis and amebiasis continue to plague the world, resulting in considerable morbidity and mortality, especially in the third world countries. These diseases are caused by a group of protozoa which have, over the years, undergone evolutionary adaptation to live often intracellularly in a parasitic way of life. So well-adapted have they become that they recognize the right hosts or cells to parasitize, yet at the same time they escape recognition and destruction by the host immune system. The mechanisms of such recognition and the escape of recognition are governed largely by host-parasite surface membrane interactions at the cellular and molecular level. Unique molecules produced by unusual pathways of these parasites have also been discovered and found to play important roles in their survival in the host. Understanding these mechanisms and pathways is essential not only to formulate a rational strategy for chemo- and immuno-prophylaxis and -therapy but also to unravel the mystery of biological evolution in symbiosis and parasitism. In the advent of our knowledge on the molecular biology and biochemistry of parasite membrane and other molecules, it is opportune to examine and discuss their possible roles in host-parasite recognition and interaction in a comparative approach. To highlight the recent advances of this area in various host-parasite systems, a NATO advanced Research Workshop was held from September 27 to October 1, 1986 at Hotel Villa del Mare, Acquafredda di Maratea, Italy.

Table of contents (2 chapter)

  • Characterization of Developmentally Regulated Molecules of Leishmania

    D. McMahon-Pratt, C. L. Jaffe, L. Kahl, P. Langer, K. Lohman, A. Pan, L. Rivas

    Pages 123-136

    Buy Chapter $29.95
  • The Microecology of Leishmania in the Gut and Proboscis of the Sandfly

    R. Killick-Kendrick

    Pages 397-406

    Buy Chapter $29.95
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Buy this book

eBook $99.00 net
( price for USA )
  • ISBN 978-3-642-72840-2
  • digitally watermarked, no DRM
  • included format: PDF
  • eBooks can be used on all Reading Devices
Softcover $129.00 net
( price for USA )
  • ISBN 978-3-642-72842-6
  • free shipping for individuals worldwide
  • usually dispatched within 3 to 5 business days

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Bibliographic Information

Bibliographic Information
Book Title
Host-Parasite Cellular and Molecular Interactions in Protozoal Infections
Series Title
Nato ASI Subseries H:
Series Volume
11
Copyright
1987
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-72840-2
DOI
10.1007/978-3-642-72840-2
Softcover ISBN
978-3-642-72842-6
Series ISSN
1010-8793
Edition Number
1
Topics