Current Topics in Microbiology and Immunology

Arenaviruses

Genes, Proteins, and Expression

Editors: Oldstone, Michael, B.A. (Ed.)

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About this book

M. B. A. OLDSTONE Viruses are generally studied either because they cause significant human, animal or plant disease or for their utility as materials to probe a basic phenomenon in biology, chemistry, genetics or molecular biology. Arenaviruses are unusually interesting in that they occupy both of these categories. Arenaviruses cause severe human diseases known primarily as the hemor­ rhagic fevers occurring in South and Latin America (Bolivia: Machupo virus and Argentina: Junin virus) and in Africa (Lassa virus). Because such viruses produce profound disability and may kill the persons they infect, they are a source of economic hardship in the countries where they are prevalent. Further, they provide new problems for health care personnel owing to the narrowing of the world as visitors from many countries increasingly travel to and from these endemic areas. In addition, lymphocytic choriomeningitis virus (LCMV) can infect humans worldwide, although the illness is most often less disabling than those elicited by other arenaviruses. Yet LCMV is likely of greater concern to non-arena-virologists and experimentalists using tissue culture or animals, i. e. , workers in molecular biology, cancer research, virology, immunobiology, etc. , because normal appearing cultured cells or tissues and animals used for research may be persistently infected with LCMV without manifesting clinical disease or cytopathology and transmit that infection to laboratory workers (reviewed OWSTONE and PETERS 1978). For example, HINMAN et al.

Table of contents (7 chapters)

  • The Arenaviruses — An Introduction

    Oldstone, M. B. A.

    Pages 1-4

  • Arenavirus Gene Structure and Organization

    Bishop, D. H. L. (et al.)

    Pages 5-17

  • Sequence Comparison Among Arenaviruses

    Southern, P. J. (et al.)

    Pages 19-39

  • Protein Structure and Expression Among Arenaviruses

    Buchmeier, M. J. (et al.)

    Pages 41-57

  • Mapping Arenavirus Genes Causing Virulence

    Riviere, Y.

    Pages 59-65

Buy this book

eBook $109.00
price for USA (gross)
  • ISBN 978-3-642-71683-6
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $149.00
price for USA
  • ISBN 978-3-642-71685-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Arenaviruses
Book Subtitle
Genes, Proteins, and Expression
Editors
  • Michael, B.A. Oldstone
Series Title
Current Topics in Microbiology and Immunology
Series Volume
133
Copyright
1987
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-71683-6
DOI
10.1007/978-3-642-71683-6
Softcover ISBN
978-3-642-71685-0
Series ISSN
0070-217X
Edition Number
1
Number of Pages
VII, 116
Topics