Systemic Lupus Erythematosus

Clinical and Experimental Aspects

Editors: Smolen, Josef, Zielinski, Christoph C. (Eds.)

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About this book

More than 140 years ago, lupus erythematosus (LE) was recognized as a disease entity by clinicians working in the field of dermatology, which had only recently become an independent medical discipline. Soon after cutaneous lupus was first reported, it was realized that, apart from the skin, the disease could involve other organs and thus be systemic in nature. The latter observations were first made by MORITZ KApOSI [1], whose work has attracted renewed attention re­ cently and who succeeded FERDINAND VON HEBRA to the chair of dermatology at the Medical Faculty in Vienna. The early description of lupus erythematosus in both its cutaneous and systemic manifes­ tations was thus intimately associated with Vienna and its Medical School. The next phase in the study of lupus was characterized by an in­ crease in knowledge of the type and extent of organ involvement. The work by OSLER [2], LIBMANN and SACKS [3], and KLEMPERER [4] best represents these advances. The increase in clinical knowledge of LE finally led to DUBOIS' famous monograph [5], which was pub­ lished at a time of renewed interest in SLE, elicited by the descrip­ tion by HARGRAVES et al. [6] of the LE-cell phenomenon. A more detailed analysis of this finding revealed that the disease was charac­ terized by an abnormal immune response, although its pathogenetic implications were still unclear.

Table of contents (19 chapters)

  • Description of Systemic Lupus Erythematosus: A Historical Perspective

    Graninger, W. (et al.)

    Pages 2-5

  • Etiologic and Pathogenetic Aspects of Systemic Lupus Erythematosus: A Critical Approach

    Graninger, W. (et al.)

    Pages 6-20

  • Genetic Aspects of Murine Lupus

    Seldin, M. F. (et al.)

    Pages 22-49

  • Autoimmune Disease in New Zealand Mice

    Chused, T. M. (et al.)

    Pages 50-59

  • The NZB × SWR Model: Insights into Viral, Immunologic, and Genetic Factors

    Datta, S. K.

    Pages 60-72

Buy this book

eBook $99.00
price for USA (gross)
  • ISBN 978-3-642-71642-3
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $129.00
price for USA
  • ISBN 978-3-642-71644-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Systemic Lupus Erythematosus
Book Subtitle
Clinical and Experimental Aspects
Editors
  • Josef Smolen
  • Christoph C. Zielinski
Copyright
1987
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
Distribution Rights
Distribution rights for Japan: Igaku Shoin, Tokao
eBook ISBN
978-3-642-71642-3
DOI
10.1007/978-3-642-71642-3
Softcover ISBN
978-3-642-71644-7
Edition Number
1
Number of Pages
XIV, 358
Topics