Environmental Toxin Series

Polychlorinated Biphenyls (PCBs): Mammalian and Environmental Toxicology

Editors: Safe, Stephen (Ed.)

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About this book

Polychlorinated biphenyls (PCBs) have been produced commercially since be­ fore 1930. They proved to be highly versatile mixtures and their uses continued to expand during the early 1970's even after the unanticipated world-wide en­ vironmental contamination had been discovered (Jensen et aI. , 1969; Koeman et aI. , 1969). Over 600,000 metric-tons were produced and/or used in the U. S. during this time and it is estimated that worldwide production totaled about 1,200,000 metric-tons (Table 1). With low acute toxicities (Fishbein, 1974), these mixtures were considered gen­ erally biologically inactive even though industrial exposure had demonstrated he­ patic and dermatological effects (Fishbein, 1974; Hansen, 1987). Thus, use and disposal were not carefully monitored and it is estimated that one-third of the world-wide production of PCBs has been released into the global environment (Table 1). Table 1. Estimated production and disposition of PCBs b U. s. a Worldwide 6 6 Production/use 610 X 10 kg 1200 X 10 kg Mobil environmental reservoir 82 400 Static reservoirs In service 340 Dumps 130 Total static 470 800 a NAS, 1979 b Tatsukawa and Tanaba, 1984 2 Environmental Distribution Many countries now impose strict controls on the use and release of PCBs. Re­ lease into the environment has declined dramatically in the last decade, but con­ tinued release from reservoirs (Table 1) into burdened ecosystems (Table 2) ap­ pears inevitable for several more decades (Barros et aI. , 1984).

Table of contents (7 chapters)

  • Polychlorinated Biphenyls: Environmental Occurrence and Analysis

    Safe, S. (et al.)

    Pages 1-13

  • Environmental Toxicology of Polychlorinated Biphenyls

    Hansen, L. G.

    Pages 15-48

  • Mammalian Biologic and Toxic Effects of PCBs

    Parkinson, A. (et al.)

    Pages 49-75

  • Carcinogenic and Mutagenic Effects of PCBs

    Hayes, M. A.

    Pages 77-95

  • Biotransformation of PCBs: Metabolic Pathways and Mechanisms

    Sipes, I. G. (et al.)

    Pages 97-110

Buy this book

eBook $109.00
price for USA (gross)
  • ISBN 978-3-642-70550-2
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $149.00
price for USA
  • ISBN 978-3-642-70552-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Polychlorinated Biphenyls (PCBs): Mammalian and Environmental Toxicology
Editors
  • Stephen Safe
Series Title
Environmental Toxin Series
Series Volume
1
Copyright
1987
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-70550-2
DOI
10.1007/978-3-642-70550-2
Softcover ISBN
978-3-642-70552-6
Series ISSN
0935-0209
Edition Number
1
Number of Pages
X, 152
Topics