Current Topics in Microbiology and Immunology

Reproductive Immunology

Editors: Olding, Lars B. (Ed.)

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About this book

Discrimination of self from nonself is the major function of the immune system and understanding the mechanism(s) involved a main employer of immunologists. Hence, the age-old puzzle of why a fetus that contains a panel of major histocompatibility (MHC) antigens derived from its mother and its father is not rejected (spontaneously aborted) by lymphocytes from its mother who should theoretically recognize foreign MHC molecules from the father has remained of great interest. This dilemma has enticed immunologists and developmental biologists for many years. This volume was created to present the information currently on hand in this subject to the scientific public. The guest editor, Professor Lars Olding, has a long and distinguished history of contributions in this field, having been one of the main propo­ nents of the argument that lymphocytes from the fetus play an active role in this process by suppressing lymphocytes from the mother from proliferating and thereby acting as killer cells. His work has defined the phenomenon and identified suppressor molecules (factors) involved in the process. In a different but related chapter, Margareta Unander extends such observations to the clinical study of women with repeated "habitual" mIS­ carriages.

Reviews

"...a dense synthesis of current knowledge of the fetomaternal interactions, contains the most recent scientific achievements, and reveals the controversial issues."
Immunology Today

Table of contents (10 chapters)

  • Immunogenetics of Reproduction:An Overview

    Ober, C. (et al.)

    Pages 1-23

  • The Structural Basis of Maternal-Fetal Immune Interactions in the Human Placenta

    Redline, R. W.

    Pages 25-44

  • Immunobiology of the Decidua

    Arck, P. C. (et al.)

    Pages 45-66

  • Ontogeny of Human Natural and Acquired Immunity

    Adinolfi, M.

    Pages 67-102

  • Maternal T Cell Reactivity in Pregnancy?

    Chaouat, G. (et al.)

    Pages 103-126

Buy this book

eBook $74.99
price for USA (gross)
  • ISBN 978-3-642-60614-4
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $99.00
price for USA
  • ISBN 978-3-642-64475-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Reproductive Immunology
Editors
  • Lars B. Olding
Series Title
Current Topics in Microbiology and Immunology
Series Volume
222
Copyright
1997
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-60614-4
DOI
10.1007/978-3-642-60614-4
Softcover ISBN
978-3-642-64475-7
Series ISSN
0070-217X
Edition Number
1
Number of Pages
XI, 223
Topics