Current Topics in Microbiology and Immunology

Vascular Growth Factors and Angiogenesis

Editors: Claesson-Welsh, Lena (Ed.)

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About this book

Currently, the cellular and molecular mechanisms governing the development and regulation of the vasculature are studied in­ tensely and the field is rapidly progressing. Recently, novel growth factors and growth factor receptors specifically acting on endothelial cells have been discovered. Through these factors, communication networks are established between endothelial cells, the basement membrane and the pericytes; this interplay is critical for the regulated development and maintenance of the vasculature. The awareness that deregulated angiogenesis con­ tributes to the progression of a number of diseases, such as cancer and inflammatory diseases, has clearly spurred the field to move forward. The focus of this book is on two important classes of endothelial cell specific growth factors, the vascular endothelial growth factor (VEGF) family, and the angiopoietins, and on their mechanisms of action. The reader will find up-to-date, fo­ cused reviews, which give the current picture, and indicate future directions. I would like to honor Dr. Judah Folkman for his important contributions to the establishment of the field and thank him for his support. Lena Claesson-Welsh List of Contents N. FERRARA Vascular Endothelial Growth Factor: Molecular and Biological Aspects . . . . . . . . . . . . . . . . . . . . . . . . . . M. G. PERSICO, V. VINCENTI and T. DIPALMA Structure, Expression and Receptor-Binding Properties of Placenta Growth Factor (PIGF) . . . . . . . . . . . . . . . . . 31 U. ERIKSSON and K. ALiTALO Structure, Expression and Receptor-Binding Properties of Novel Vascular Endothelial Growth Factors. . . . . . . . . 41 M. SHIBUYA, N. ITo and L. CLAESSON-WELSH Structure and Function of Vascular Endothelial Growth Factor Receptor-I and -2 . . . . . . . . . . . . . . . . . . 59 J. TAIPALE, T. MAKINEN, E. ARIGHI, E.

Table of contents (10 chapters)

  • Vascular Endothelial Growth Factor: Molecular and Biological Aspects

    Ferrara, N.

    Pages 1-30

  • Clostridium difficile Infection in Humans and Piglets: A ‘One Health’ Opportunity

    Michele M. Squire, Thomas V. Riley

    Pages 1-16

  • Structure, Expression and Receptor-Binding Properties of Placenta Growth Factor (PlGF)

    Persico, M. G. (et al.)

    Pages 31-40

  • Structure, Expression and Receptor-Binding Properties of Novel Vascular Endothelial Growth Factors

    Eriksson, U. (et al.)

    Pages 41-57

  • Structure and Function of Vascular Endothelial Growth Factor Receptor-1 and -2

    Shibuya, M. (et al.)

    Pages 59-83

Buy this book

eBook n/a
  • ISBN 978-3-642-59953-8
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
Softcover n/a
  • ISBN 978-3-642-64195-4
  • Free shipping for individuals worldwide
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Bibliographic Information

Bibliographic Information
Book Title
Vascular Growth Factors and Angiogenesis
Editors
  • Lena Claesson-Welsh
Series Title
Current Topics in Microbiology and Immunology
Series Volume
237
Copyright
1999
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-59953-8
DOI
10.1007/978-3-642-59953-8
Softcover ISBN
978-3-642-64195-4
Series ISSN
0070-217X
Edition Number
1
Number of Pages
IX, 189
Number of Illustrations and Tables
2 illustrations in colour
Topics