Research and Perspectives in Neurosciences

Neuro-Immune Interactions in Neurologic and Psychiatric Disorders

Editors: Patterson, P., Kordon, C., Christen, Y. (Eds.)

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  • ISBN 978-3-642-59643-8
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About this book

This book arrives at the moment when the role of inflammatory processes in neurodegenerative disease, mental illness, and injury is starting to become more widely appreciated. As summarized in these chapters from some of the major laboratories in the field, not only can the brain interact actively with the immune system, but it can generate its own inflammatory responses to stress, certain diseases, and other insults. The contribution of cytokines and other inflammatory molecules to Alzheimer's disease is highlighted here, as is the key importance of the brains's own inflammatory cells, the microglia. Such studies in cell culture and in animal models clearly have the potential to influence clinical practice. The two-way communication between the brain and the immune system is emphasized by experiments showing that infection in peripheral tissues can cause dramatic changes in behavior of animals, while behavioral states such as severe depression can induce marked changes in immune function. These molecular and anatomical bases for such interactions are becoming understood, which will ultimately have therapeutic implications.

Table of contents (17 chapters)

  • Organization of Inflammatory Processes in Alzheimer’s Disease

    Rogers, J. (et al.)

    Pages 1-7

  • Glial Cytokines in Neurodegenerative Conditions

    Mrak, R. E. (et al.)

    Pages 9-17

  • Contributions of the Glial Injury Response to the Multifactorial Pathogenesis of Alzheimer’s Disease

    Mucke, L. (et al.)

    Pages 19-33

  • Cytokine Communication Between Neurons and Glia and the Pathogenesis of Alzheimer’s Disease

    Cordell, B. (et al.)

    Pages 35-46

  • Glial Hyperactivity During Aging as a Neuroinflammatory Process

    Finch, C. E. (et al.)

    Pages 47-56

Buy this book

eBook $109.00
price for USA (gross)
  • ISBN 978-3-642-59643-8
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $149.00
price for USA
  • ISBN 978-3-642-64065-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Neuro-Immune Interactions in Neurologic and Psychiatric Disorders
Editors
  • P. Patterson
  • C. Kordon
  • Y. Christen
Series Title
Research and Perspectives in Neurosciences
Copyright
2000
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-59643-8
DOI
10.1007/978-3-642-59643-8
Softcover ISBN
978-3-642-64065-0
Series ISSN
0945-6082
Edition Number
1
Number of Pages
XIV, 204
Number of Illustrations and Tables
6 illustrations in colour
Topics