Recent Results in Cancer Research

Lymphatic Metastasis and Sentinel Lymphonodectomy

Editors: Schlag, P.M., Veronesi, Umberto (Eds.)

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About this book

Metastases determine malignancy. The main attention so far has been focused upon organ metastases. The molecular mechanisms thereof, while far from being totally elucidated, are increasingly well understood. Modern diagnostic tools now enable detection and precise localization of small lesions. In contrast, our knowl­ edge and diagnostic capabilities regarding metastatic spread to the'lymphatic system are rather limited. However, there have re­ cently been a number of interesting advances. It is the aim of this volume to submit these developments to detailed analysis. The therapeutic relevance of enhanced sensitivity in detection of lymph node metastases has to be considered in the light of in­ creased morbidity versus eventual prognostic improvements by modification of therapy. An interesting concept which might im­ prove diagnostic accuracy while reducing operative morbidity is the "sentinel node" technique. Surgical standards are lacking, however, and many fundamental questions pertaining to precise lymphatic mapping remain unanswered. Whether the sentinel node concept is of general relevance or whether it is applicable in only a few organs remains to be determined. This book offers intensive discussion of the concept from methodological and tu­ mor biological viewpoints. World-renowned experts with long­ term involvement in related basic and clinical research provide the reader with a broad survey of actual knowledge together with a critical appraisal of recent and future developments. We sincerely hope this book succeeds in providing an outlook as a reference for all clinicians on future prospects and serving and researchers in this extremely important field.

Table of contents (26 chapters)

  • Efficacy of Immunoscintigraphy for Detection of Lymph Node Metastases

    Britton, K. E. (et al.)

    Pages 3-11

  • Sensitivity and Specificity of Positron Emission Tomography (PET) for the Diagnosis of Lymph Node Metastases

    Strauss, L. G.

    Pages 12-19

  • Diagnosis and Staging of Lymph Node Metastasis

    Wittekind, Ch.

    Pages 20-28

  • Detection and Relevance of Immunohistochemically Identifiable Tumor Cells in Lymph Nodes

    Passlick, B. (et al.)

    Pages 29-37

  • Cell Biology of Lymphatic Metastasis The Potential Role of c-erbB Oncogene Signalling

    Eccles, S. A.

    Pages 41-54

Buy this book

eBook $74.99
price for USA (gross)
  • ISBN 978-3-642-57151-0
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $99.00
price for USA
  • ISBN 978-3-642-63070-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Lymphatic Metastasis and Sentinel Lymphonodectomy
Editors
  • P.M. Schlag
  • Umberto Veronesi
Series Title
Recent Results in Cancer Research
Series Volume
157
Copyright
2000
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin · Heidelberg
eBook ISBN
978-3-642-57151-0
DOI
10.1007/978-3-642-57151-0
Softcover ISBN
978-3-642-63070-5
Series ISSN
0080-0015
Edition Number
1
Number of Pages
XII, 309
Number of Illustrations and Tables
61 b/w illustrations, 2 illustrations in colour
Topics