Recent Results in Cancer Research

Tumor Prevention and Genetics

Editors: Senn, Hans-Jörg, Morant, Rudolf (Eds.)

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About this book

Hans-Jorg Senn H.-J. Senn (~) Center for Tumor Detection and Prevention, Rorschacherstr. 150, CH-9006 St. Gallen, Switzerland Clinical oncology has centered mainly on developing new strategies and a multitude of new drugs for fighting relapsing and progressive cancer during the last two decades. Furthermore, it has done this with respectable success in quite a number of neoplastic diseases such as acute leukemias and sarcomas in pediatric patients and certain types of aggressive lymphomas, as well as se­ lected solid tumors such as testicular cancer and choriocarcinoma in adult age. Curatively intended adjuvant chemo-and endocrine-therapies of several "main killers" among prevalent cancer types, especially breast and colon can­ cer, have also become successful and health-politically meaningful therapeutic targets [1, 2]. However, the net gain in "cure" of these (mostly pharmacologic) therapeu­ tic approaches has to be realistically judged as having a moderate impact on the cancer problem as a whole, and the mortality rate of the most frequent tu­ mor types, which are prevalent in adult life, has with very few exceptions not been substantially decreased over the past two to three decades. Increasingly, health politicians, epidemiologists, and medical journal editors are asking for alternative strategies of lowering cancer incidence and increasing survival, ventilating new and hitherto mostly neglected areas of research such as pri­ mary and secondary cancer prevention.

Table of contents (24 chapters)

  • Introduction

    Senn, Hans-Jörg

    Pages 1-3

  • Genetic Susceptibility, Predicting Risk and Preventing Cancer

    Pharoah, Paul D. P.

    Pages 7-18

  • Novel Approaches to Identify Low-Penetrance Cancer Susceptibility Genes Using Mouse Models

    Koning, John P. (et al.)

    Pages 19-27

  • Development of Novel Selective Cell Ablation in the Mammary Gland and Brain to Study Cell-Cell Interactions and Chemoprevention

    Gusterson, Barry A. (et al.)

    Pages 31-45

  • Mouse Skin as a Model for Cancer Chemoprevention by Nonsteroidal Anti-Inflammatory Drugs

    Marks, Friedrich (et al.)

    Pages 46-57

Buy this book

eBook $99.00
price for USA (gross)
  • ISBN 978-3-642-55647-0
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $129.00
price for USA
  • ISBN 978-3-642-62892-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Tumor Prevention and Genetics
Editors
  • Hans-Jörg Senn
  • Rudolf Morant
Series Title
Recent Results in Cancer Research
Series Volume
163
Copyright
2003
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-55647-0
DOI
10.1007/978-3-642-55647-0
Softcover ISBN
978-3-642-62892-4
Series ISSN
0080-0015
Edition Number
1
Number of Pages
VII, 266
Topics