Molecular Basis of Breast Cancer

Prevention and Treatment

Authors: Russo, Jose, Russo, Irma H.

  • Up-to-date information on the molecular basis of breast cancer
  • Extremely helpful both for clinicians treating patients and for researchers looking for new venues of development
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eBook $99.00
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  • ISBN 978-3-642-18736-0
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  • Included format: PDF
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  • Immediate eBook download after purchase
Softcover $134.00
price for USA
  • ISBN 978-3-642-62270-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

book, whose goal is to comprehensively review in ten During the past 30 years we have witnessed the emer­ chapters the fundamental knowledge on breast can­ gence of new disciplines whose contribution to the understanding of the biology of breast cancer have cer. The opening chapter links epidemiology, influ­ been enormous. Advances in the field of steroid hor­ ence of geographic and environmental exposures on mone nuclear receptors, which control the expression cancer incidence to the development of the organ and of genetic programs involved in cellular processes its role in cancer initiation. Central to this approach that are essential for normal and aberrant cell is the endocrine control of breast development, the growth, have been major contributors to the therapy relationship of cell proliferation with the presence of and prevention of hormone-dependent cancers. The steroid hormone receptors in the breast epithelium, and finally the importance of full differentiation as a discoveries of the association of hereditary breast cancers with mutations in the BRCAl and BRCA2 tool for protecting the breast from developing cancer. genes, and the concept that they essentially represent Reported are studies of the pathogenesis of breast a continuum of mutations with different degrees of cancer that have elucidated the site of origin of breast penetrance within given families, have added consid­ cancer and have been validated by in vitro experi­ erable understanding to the molecular basis of breast mentation.

Reviews

From the reviews:

"This book provides the scientific basis for a new paradigm according to which breast cancer prevention and treatment should be developed. The book is unique in that it is based on an understanding of the developmental pattern of the breast in rodents and humans." (Biomedicine & Pharmacotherapy, Vol. 58, 2004)

"This is a comprehensive and detailed textbook which covers all the fundamental areas of knowledge on breast cancer. … This text provides an excellent reference book for anyone involved in this field … . For those wanting an in-depth knowledge of this rapidly expanding field, this is easy to read and tackles complex theories very successfully with excellent illustrations to all chapters." (Erika Denton, RAD Magazine, September, 2004)

"Molecular Basis of Breast Cancer provides a window through which to view some future strategies in the prevention of breast cancer. This richly illustrated book has a unique focus and original perspective. … The broad summary of the scientific literature on this area of research strongly adds value to the book." (Robert B. Dickson, The New England Journal of Medicine, Issue 9, 2004)


Table of contents (10 chapters)

  • Epidemiological Considerations in Breast Cancer

    Russo, Jose (et al.)

    Pages 1-9

  • The Breast as a Developing Organ

    Russo, Jose (et al.)

    Pages 11-48

  • Endocrine Control of Breast Development

    Russo, Jose (et al.)

    Pages 49-88

  • The Role of Estrogen in Breast Cancer

    Russo, Jose (et al.)

    Pages 89-135

  • Pathogenesis of Breast Cancer

    Russo, Jose (et al.)

    Pages 137-180

Buy this book

eBook $99.00
price for USA (gross)
  • ISBN 978-3-642-18736-0
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $134.00
price for USA
  • ISBN 978-3-642-62270-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Molecular Basis of Breast Cancer
Book Subtitle
Prevention and Treatment
Authors
Copyright
2004
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-18736-0
DOI
10.1007/978-3-642-18736-0
Softcover ISBN
978-3-642-62270-0
Edition Number
1
Number of Pages
XIV, 448
Number of Illustrations and Tables
225 b/w illustrations, 1278 illustrations in colour
Topics