Current Topics in Microbiology and Immunology

High-Dimensional Single Cell Analysis

Mass Cytometry, Multi-parametric Flow Cytometry and Bioinformatic Techniques

Editors: Fienberg, Harris G., Nolan, Garry P. (Eds.)

  • Addresses most interesting questions and applications enabled by high dimensional flow cytometry
  • Reviews current practical approaches used to perform mass cytometry experiments
  • Covers key bioinformatic techniques developed to facilitate analysis of data sets involving dozens of parameters in millions of single cells
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eBook $149.00
price for USA (gross)
  • ISBN 978-3-642-54827-7
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $189.00
price for USA
  • ISBN 978-3-642-54826-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $189.00
price for USA
  • ISBN 978-3-662-51267-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This volume highlights the most interesting biomedical and clinical applications of high-dimensional flow and mass cytometry. It reviews current practical approaches used to perform high-dimensional experiments and addresses key bioinformatic techniques for the analysis of data sets involving dozens of parameters in millions of single cells. Topics include single cell cancer biology; studies of the human immunome; exploration of immunological cell types such as CD8+ T cells; decipherment of signaling processes of cancer; mass-tag cellular barcoding; analysis of protein interactions by proximity ligation assays; Cytobank, a platform for the analysis of cytometry data; computational analysis of high-dimensional flow cytometric data; computational deconvolution approaches for the description of intracellular signaling dynamics and hyperspectral cytometry. All 10 chapters of this book have been written by respected experts in their fields. It is an invaluable reference book for both basic and clinical researchers.

Table of contents (10 chapters)

  • High-Dimensional Single-Cell Cancer Biology

    Irish, Jonathan M. (et al.)

    Pages 1-21

  • Studying the Human Immunome: The Complexity of Comprehensive Leukocyte Immunophenotyping

    Biancotto, Angélique (et al.)

    Pages 23-60

  • High-Dimensional Analysis of Human CD8+ T Cell Phenotype, Function, and Antigen Specificity

    Newell, Evan W. (et al.)

    Pages 61-84

  • Mass Cytometry to Decipher the Mechanism of Nongenetic Drug Resistance in Cancer

    Fienberg, Harris G. (et al.)

    Pages 85-94

  • A Practical Guide to Multiplexed Mass Cytometry

    Zivanovic, Nevena (et al.)

    Pages 95-109

Buy this book

eBook $149.00
price for USA (gross)
  • ISBN 978-3-642-54827-7
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $189.00
price for USA
  • ISBN 978-3-642-54826-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $189.00
price for USA
  • ISBN 978-3-662-51267-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
High-Dimensional Single Cell Analysis
Book Subtitle
Mass Cytometry, Multi-parametric Flow Cytometry and Bioinformatic Techniques
Editors
  • Harris G. Fienberg
  • Garry P. Nolan
Series Title
Current Topics in Microbiology and Immunology
Series Volume
377
Copyright
2014
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-54827-7
DOI
10.1007/978-3-642-54827-7
Hardcover ISBN
978-3-642-54826-0
Softcover ISBN
978-3-662-51267-8
Series ISSN
0070-217X
Edition Number
1
Number of Pages
X, 215
Number of Illustrations and Tables
1 b/w illustrations, 67 illustrations in colour
Topics