RNA Technologies

Chemical Biology of Nucleic Acids

Fundamentals and Clinical Applications

Editors: Erdmann (Deceased), Volker A., Markiewicz, Wojciech T., Barciszewski, Jan (Eds.)

  • Detailed and comprehensive overview of the various different RNA species
  • Bench to bedside approach
  • Written by leading authorities in the field
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eBook $189.00
price for USA (gross)
  • ISBN 978-3-642-54452-1
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $239.00
price for USA
  • ISBN 978-3-642-54451-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $239.00
price for USA
  • ISBN 978-3-662-51324-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This volume contains 29 engrossing chapters contributed by worldwide, leading research groups in the field of chemical biology. Topics include pre-biology; the establishment of the genetic code; isomerization of RNA; damage of nucleobases in RNA; the dynamic structure of nucleic acids and their analogs in DNA replication, extra- and intra-cellular transport; molecular crowding by the use of ionic liquids; new technologies enabling the modification of gene expression via editing of therapeutic genes; the use of riboswitches; the modification of mRNA cap regions; new approaches to detect appropriately modified RNAs with EPR spectroscopy and the use of parallel and high-throughput techniques for the analysis of the structure and new functions of nucleic acids. This volume discusses how chemistry can add new frontiers to the field of nucleic acids in molecular medicine, biotechnology and nanotechnology and is not only an invaluable source of information to chemists, biochemists and life scientists but will also stimulate future research.

Table of contents (29 chapters)

  • RNA as Major Components in Chemical Evolvable Systems

    Strazewski, Peter

    Pages 1-24

  • How the Early Genetic Code Was Established?: Inference from the Analysis of Extant Animal Mitochondrial Decoding Systems

    Watanabe, Kimitsuna (et al.)

    Pages 25-40

  • Isomerization of RNA Phosphodiester Linkages

    Lönnberg, Harri

    Pages 41-56

  • Effects of Ionic Liquid and Liposomes on the Structure, Stability, and Function of Nucleic Acids

    Sugimoto, Naoki

    Pages 57-74

  • Oxidative Damage on RNA Nucleobases

    Küpfer, Pascal A. (et al.)

    Pages 75-94

Buy this book

eBook $189.00
price for USA (gross)
  • ISBN 978-3-642-54452-1
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $239.00
price for USA
  • ISBN 978-3-642-54451-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $239.00
price for USA
  • ISBN 978-3-662-51324-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Chemical Biology of Nucleic Acids
Book Subtitle
Fundamentals and Clinical Applications
Editors
  • Volker A. Erdmann (Deceased)
  • Wojciech T. Markiewicz
  • Jan Barciszewski
Series Title
RNA Technologies
Copyright
2014
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-54452-1
DOI
10.1007/978-3-642-54452-1
Hardcover ISBN
978-3-642-54451-4
Softcover ISBN
978-3-662-51324-8
Series ISSN
2197-9731
Edition Number
1
Number of Pages
XI, 599
Number of Illustrations and Tables
147 b/w illustrations, 84 illustrations in colour
Topics