Cardiovascular and Cardiac Therapeutic Devices

1. Front Matter

   Pages i-viii

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2. Multi-Objective Design of a Biodegradable Coronary Artery Stent

   • Neil W. Bressloff

   Pages 1-28

3. Development of a Fabric-Reinforced Porous Graft for Vascular Tissue Engineering Using Finite Element Methods and Genetic Algorithms

   • Mark S. Yeoman, B. Daya Reddy, Deon Bezuidenhout, Hellmut C. Bowles, Peter Zilla, Thomas Franz

   Pages 29-61

4. Aortic Aneurysms: OSR, EVAR, Stent-Grafts, Migration and Endoleak—Current State of the Art and Analysis

   • Shahid Manzoor Toor, Igor Sazonov, Heyman Luckraz, Perumal Nithiarasu

   Pages 63-92

5. Flexible Leaflet Polymeric Heart Valves

   • Deon Bezuidenhout, Peter Zilla

   Pages 93-129

6. Aortic Biological Prosthetic Valve for Open-Surgery and Percutaneous Implant: Procedure Simulation and Performance Assessment

   • Ferdinando Auricchio, Michele Conti, Simone Morganti

   Pages 131-168

7. Cardiac Restraint and Support Following Myocardial Infarction

   • Samantha A. Clarke, Ravi K. Ghanta, Gorav Ailawadi, Jeffrey W. Holmes

   Pages 169-206

8. In Vivo Mechanical Loading Conditions of Pectorally Implanted Cardiac Pacemakers

   • Thomas Franz, Michael Hamman de Vaal, James Neville, Jacques Scherman, Micah Litow, Peter Zilla

   Pages 207-237

9. Errata to: In Vivo Mechanical Loading Conditions of Pectorally Implanted Cardiac Pacemakers

   • Thomas Franz, Michael Hamman de Vaal, James Neville, Jacques Scherman, Micah Litow, Peter Zilla

   Pages 239-239

10. Errata to: Development of a Fabric-Reinforced Porous Graft for Vascular Tissue Engineering Using Finite Element Methods and Genetic Algorithms

    • Mark S. Yeoman, B. Daya Reddy, Deon Bezuidenhout, Hellmut C. Bowles, Peter Zilla, Thomas Franz

    Pages 241-241

11. Back Matter

    Pages 243-243

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This volume focuses on latest research in therapeutic devices for cardiovascular, i.e. vascular and valvular and cardiac diseases. In the area of vascular therapies, aspects covered relate to latest research in small-diameter tissue-regenerative vascular grafts, one of the greatest persisting challenges in cardiovascular therapies, stent grafts and endovascular stents for percutaneous arterial interventions. Contributions on valvular therapies focus on tissue engineered and tissue regenerative prosthetic heart valves and valvular prostheses for trans-apical implantation including the challenges posed on the prosthesis design. The section on cardiac diseases aims at covering therapeutic advances for myocardial infarction and prevention of heart failure and on in vivo biomechanics of implantable cardiac pacemaker devices. A further section complements these three areas by presenting constitutive modelling of soft biological tissues of the cardiovascular system, an area imperative for advanced numerical and computational modelling in the development and optimisation of cardiovascular devices and therapies.

• Endovascular Stents for Percutaneous Arterial Interventions
• Implantable Cardiac Pacemaker Devices
• Modelling of Soft Biological Tissues
• Myocardial Infarction
• Prostheses for Transapical Implantation
• Small-diameter Vascular Graft
• Tissue Regenerative Prosthetic Heart Valves
• Tissue-regenerative Vascular Graft

From the book reviews:

“This book focuses on cardiovascular and cardiac therapeutic devices and covers current research in this area. It covers in detail stents, grafts, prosthetic heart valves, and pacemakers and includes a detailed discussion of the state of the art of these devices. With very detailed discussions about these highly specialized areas of investigation, this book is intended primarily for researchers.” (Michael Bates, Doody’s Book Reviews, August, 2014)

• Faculty of Health Sciences and Research Office, University of Cape Town, Cape Town, South Africa

  Thomas Franz

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