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Gene Vaccination: Theory and Practice

  • Book
  • © 1998

Overview

Editors:
  1. Eyal Raz

    1. Department of Medicine, University of California, San Diego, La Jolla, USA

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Part of the book series: Principles and Practice (PRINCIPLES)

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Table of contents (15 chapters)

  1. Front Matter

    Pages I-X
    Download chapter PDF

  2. Introduction: gene vaccination, current concepts and future directions

    • Eyal Raz
    Pages 1-7

  3. Plasmid DNA vaccination: mechanism of antigen presentation

    • Maripat Corr, Helen Tighe
    Pages 9-15

  4. The development of a multivalent DNA vaccine for malaria

    • Richard C. Hedstrom, Denise L. Doolan, Ruobing Wang, Malcolm J. Gardner, Anita Kumar, Martha Sedegah et al.
    Pages 17-29

  5. Genetic adjuvants for DNA immunization

    • Robert B. Mendoza, Thomas J. Kipps
    Pages 31-38

  6. Gene immunization for the induction of antigen-specific, non MHC-restricted responses

    • Delphine J. Lee, Dennis A. Carson, Maripat Corr
    Pages 39-49

  7. DNA vaccines with rapid intracellular degradation are more effective for inducing CTL

    • Yunqi Wu, Thomas J. Kipps
    Pages 51-57

  8. Genetic vaccination against tuberculosis

    • Douglas B. Lowrie, Celio L. Silva, Ricardo E. Tascon
    Pages 59-71

  9. DNA gene vaccination for HIV

    • Jong J. Kim, David B. Weiner
    Pages 73-92

  10. DNA-based immunization against hepatitis B virus

    • Heather L. Davis, Cynthia L. Brazolot Millan
    Pages 93-107

  11. Gene vaccination for hepatitis C

    • Geneviève Inchauspé
    Pages 109-119

  12. Gene immunization for allergic disorders

    • Mark Roman, Hans L. Spiegelberg, David Broide, Eyal Raze
    Pages 121-130

  13. Immunization with DNA vaccines in early life: advantages and limitations as compared to conventional vaccines

    • Claire-Anne Siegrist, Paul-Henri Lambert
    Pages 131-141

  14. DNA vaccination by somatic transgene immunization

    • Maurizio Zanetti, Sidong Xiong, Mara Gerloni
    Pages 143-156

  15. DNA vaccines: safety and efficacy issues

    • Dennis M. Klinman, Mitsuhiro Takeno, Motohide Ichino, Mili Gu, Galina Yamshchikov, Gil Mor et al.
    Pages 157-168

  16. Genetic vaccines — a revolution in vaccinology?

    • Z. Q. Xiang, S. Pasquini, Z. He, H. Deng, Y. Wang, M. A. Blaszczyk-Thurin et al.
    Pages 169-180
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Keywords

About this book

Vaccination has been established as an efficient procedure to prevent infections. Over the past few years, a new method of subunit vaccination has attracted the attention of immunologists. Despite its popularity, it is only recently that the basic mechanisms that drive the immune response to the encoded antigen have begun to unfold. The multidisciplinary approach of this book outlines the basic characteristics of gene (DNA) vaccination, the role of APCs or bone marrow derived cells in the induction of the immune response. It points out the potential applications for various infectious and allergic diseases and describes the multifaceted properties of DNA in initiating and determining the subsequent immune responses to the encoded antigen.

Editors and Affiliations

  • Department of Medicine, University of California, San Diego, La Jolla, USA

    Eyal Raz

Bibliographic Information

  • Book Title: Gene Vaccination: Theory and Practice

  • Editors: Eyal Raz

  • Series Title: Principles and Practice

  • DOI: https://doi.org/10.1007/978-3-642-46867-4

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1998

  • Softcover ISBN: 978-3-642-46869-8Published: 25 February 2012

  • eBook ISBN: 978-3-642-46867-4Published: 06 December 2012

  • Series ISSN: 1866-914X

  • Series E-ISSN: 1866-9158

  • Edition Number: 1

  • Number of Pages: X, 180

  • Number of Illustrations: 4 illustrations in colour

  • Additional Information: Originally published in the Journal "Springer Seminars in Immunopathology", Vol 19, Number 2, 1997

  • Topics: Human Genetics, Immunology, Medical Microbiology, Molecular Medicine

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