Bacteria and Complement

1. Front Matter

   Pages i-ix

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2. Bacteria and Complement — A Historical Review

   • M. Loos

   Pages 1-5

3. The Complement System: Activation and Control

   • M. Loos

   Pages 7-18

4. The Role of the Classical Pathway for the Bactericidal Effect of Normal Sera Against Gram-Negative Bacteria

   • F. Clas, G. Schmidt, M. Loos

   Pages 19-72

5. Evidence for Direct Binding of the First Component of Complement, C1, to Outer Membrane Proteins from Salmonella minnesota

   • F. Stemmer, M. Loos

   Pages 73-84

6. Differences in Attachment and Phagocytosis of Salmonella minnesota Strains (S Form, Re Mutant) by Mouse Peritoneal Macrophages: Participation of Endogenous C1q and Bacterial Surface Components (LPS, Porins)

   • B. Euteneuer, S. Störkel, M. Loos

   Pages 85-97

7. Studies on the Mechanism of Bacterial Resistance to Complement-Mediated Killing and on the Mechanism of Action of Bactericidal Antibody

   • K. A. Joiner

   Pages 99-133

8. Effect of Lethal Doses of Complement on the Functional Integrity of Target Enterobacteria

   • P. W. Taylor, H.-P. Kroll

   Pages 135-158

9. Interaction of Gram-Positive Microorganisms with Complement

   • E. J. Brown

   Pages 159-187

10. Back Matter

    Pages 189-191

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Deficiencies in any of the defense mechanisms of the host can lead to severe microbial infections; these are of clinical relevance. Broad up-to-date knowledge in this field allows identification of many unspecific as well as highly specific defense reactions involved in the struggle against infectious diseases. On the other hand, protective structures on the microbial cell surfaces have been adapted and improve the counterpart's chances of survival. In particular, it has been considered that the great diversity of the bacterial envelopes not only determines the anatomical location of the tissue injury but also induces activation of distinct parts of the complex defense system. The specific defense mechanism, whose most prominent constituent is provided by the antibo

• bacteria
• cell
• diseases
• infection
• infections
• infectious disease

• Institut für Medizinische Mikrobiologie, Johannes-Gutenberg-Universität, Mainz, Germany

  Michael Loos

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