Treatment–Refractory Schizophrenia

A Clinical Conundrum

Editors: Buckley, Peter F., Gaughran, Fiona (Eds.)

  • Comprehensive, clinically focused guide to the treatment of the most severely ill patients with schizophrenia
  • Informed by the latest research findings on neurobiology and treatment
  • Written by leading experts from Europe and the Americas
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About this book

Schizophrenia is often associated with an inadequate response to pharmacological and non-pharmacological treatments. How to treat patients who have an unsatisfactory response to anti-psychotics, including clozapine - which is unequivocally the most powerful antipsychotic medication for this recalcitrant population  - remains a clinical conundrum. A range of adjunctive medications have been tried with mixed results; there has also been renewed interest in the role of neuromodulatory strategies, electroconvulsive therapy, and cognitive and vocational approaches. Perhaps a bright spot for the future lies in the evolution of pharmacogenetic approaches for individualized care.

In this book, leading experts from Europe, Australia and the Americas provide a timely appraisal of treatments for the most severely ill schizophrenia patients. This clinically focused  book is informed by the latest research on the neurobiology and treatment of schizophrenia. It is comprehensive in scope, covering current treatment options, various add-on approaches, and a range of psychosocial treatments. The contributors are respected experts who have combined their clinical experience with cutting-edge research to provide readers with authoritative information on fundamental aspects of clinical care for schizophrenia.

Reviews

“This book is an excellent collection of chapters that collectively comprise the clinical and scientific knowledge base about refractory schizophrenia. … For psychiatric practitioners, both prescribers and therapists, who manage schizophrenia on a daily basis, this book is a must own reference because of the wealth of helpful information between the covers.” (Henry A. Nasrallah, Journal of Clinical Psychiatry, Vol. 76 (9), September, 2015)

“This interesting book reviews treatment strategies and management options for those suffering from treatment-refractory schizophrenia (TRS). … The target audience includes psychiatrists and other mental health professionals. Any clinicians who treat severely ill patients with psychiatric disorders would benefit from reading this book. … This is an exceptional book covering a current critical issue for psychiatry and the patients suffering from unremitting psychosis. I highly recommend it.” (Michael Joel Schrift, Doody’s Book Reviews, July, 2014)

Table of contents (13 chapters)

  • Treatment-Refractory Schizophrenia: Definition and Assessment

    Tracy, Derek K. (et al.)

    Pages 1-19

  • Biology of Schizophrenia: Is Treatment Refractoriness Synonymous with Severity of Illness [A.K.A. Is This a Drug Efficacy Problem or an Expression of Severe Illness?]

    Elkis, Helio (et al.)

    Pages 21-30

  • Dopamine and the Biology and Course of Treatment Resistance

    Demjaha, Arsime (et al.)

    Pages 31-43

  • Medical and Psychiatric Comorbidities: Complicating Treatment Expectations

    Miller, Brian J. (et al.)

    Pages 45-63

  • Overview of Pharmacological Treatments and Guidelines

    Gee, Siobhan (et al.)

    Pages 65-80

Buy this book

eBook $44.99
price for USA (gross)
  • ISBN 978-3-642-45257-4
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $59.99
price for USA
  • ISBN 978-3-642-45256-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $59.99
price for USA
  • ISBN 978-3-662-52387-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Rent the ebook  
  • Rental duration: 1 or 6 month
  • low-cost access
  • online reader with highlighting and note-making option
  • can be used across all devices
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Bibliographic Information

Bibliographic Information
Book Title
Treatment–Refractory Schizophrenia
Book Subtitle
A Clinical Conundrum
Editors
  • Peter F. Buckley
  • Fiona Gaughran
Copyright
2014
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-45257-4
DOI
10.1007/978-3-642-45257-4
Hardcover ISBN
978-3-642-45256-7
Softcover ISBN
978-3-662-52387-2
Edition Number
1
Number of Pages
VIII, 230
Number of Illustrations and Tables
1 b/w illustrations, 6 illustrations in colour
Topics