Handbook of Experimental Pharmacology

Arrestins - Pharmacology and Therapeutic Potential

Editors: Gurevich, Vsevolod V. (Ed.)

  • Discusses therapeutic potential of biased ligands of G protein-coupled receptors
  • Describes the molecular mechanisms and therapeutic implications of arrestin-mediated signaling
  • Discusses the potential of reengineered signaling proteins for gene therapy  
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eBook $329.00
price for USA (gross)
  • ISBN 978-3-642-41199-1
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $419.00
price for USA
  • ISBN 978-3-642-41198-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $419.00
price for USA
  • ISBN 978-3-662-52299-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This volume describes our current understanding of the biological role of visual and non-visual arrestins in different cells and tissues, focusing on the mechanisms of arrestin-mediated regulation of GPCRs and non-receptor signaling proteins in health and disease. The book covers wide range of arrestin functions, emphasizing therapeutic potential of targeting arrestin interactions with individual partners.

Table of contents (22 chapters)

  • Therapeutic Potential of Small Molecules and Engineered Proteins

    Gurevich, Eugenia V. (et al.)

    Pages 1-12

  • Arrestin Interactions with G Protein-Coupled Receptors

    Lohse, Martin J. (et al.)

    Pages 15-56

  • Quantifying Biased β-Arrestin Signaling

    Kenakin, Terry

    Pages 57-83

  • The Physiological Roles of Arrestin-1 in Rod Photoreceptor Cells

    Chen, Jeannie

    Pages 85-99

  • Not Just Signal Shutoff: The Protective Role of Arrestin-1 in Rod Cells

    Sommer, Martha E. (et al.)

    Pages 101-116

Buy this book

eBook $329.00
price for USA (gross)
  • ISBN 978-3-642-41199-1
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $419.00
price for USA
  • ISBN 978-3-642-41198-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $419.00
price for USA
  • ISBN 978-3-662-52299-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Arrestins - Pharmacology and Therapeutic Potential
Editors
  • Vsevolod V. Gurevich
Series Title
Handbook of Experimental Pharmacology
Series Volume
219
Copyright
2014
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-41199-1
DOI
10.1007/978-3-642-41199-1
Hardcover ISBN
978-3-642-41198-4
Softcover ISBN
978-3-662-52299-8
Series ISSN
0171-2004
Edition Number
1
Number of Pages
VIII, 447
Number of Illustrations and Tables
11 b/w illustrations, 42 illustrations in colour
Topics