Current Topics in Microbiology and Immunology

Pathogenesis of Mycobacterium tuberculosis and its Interaction with the Host Organism

Editors: Pieters, Jean, McKinney, John D. (Eds.)

  • A stimulus for the further exploration of the intricate biology of Mycobacterium tuberculosis and its interaction with the host
  • Written by respected experts from different disciplines
  • Richly illustrated
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eBook $149.00
price for USA (gross)
valid through November 5, 2017
  • ISBN 978-3-642-40232-6
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Hardcover $189.00
price for USA
valid through November 5, 2017
  • ISBN 978-3-642-40231-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $189.00
price for USA
valid through November 5, 2017
  • ISBN 978-3-662-52142-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Mycobacterium tuberculosis is one of the most notorious pathogens on earth, causing the death of approximately 1.5 million people annually. A major problem in the fight against tuberculosis is the emergence of strains that have acquired resistance to all available antibiotics. One key to the success of M. tuberculosis as a pathogen is its ability to circumvent host immune responses at different levels. This is not only a result of the special makeup of M. tuberculosis in terms of genetic diversity and DNA metabolism and its possession of specialized secretion systems, but also of its ability to hijack the host’s innate immune defence mechanisms.

In this volume, researchers from different disciplines provide a topical overview of the diverse mechanisms that contribute to the virulence of M. tuberculosis, ranging from their genetic, metabolic and molecular makeup, as well as the complex strategies these bacteria utilize to escape immune destruction within infected hosts.

Table of contents (9 chapters)

  • Genetic Diversity in Mycobacterium tuberculosis

    Gagneux, Sebastien

    Pages 1-25

  • DNA Metabolism in Mycobacterial Pathogenesis

    Warner, Digby F. (et al.)

    Pages 27-51

  • Molecular Biology of Drug Resistance in Mycobacterium tuberculosis

    Smith, Tasha (et al.)

    Pages 53-80

  • Antimicrobial Efflux Pumps and Mycobacterium tuberculosis Drug Tolerance: Evolutionary Considerations

    Szumowski, John D. (et al.)

    Pages 81-108

  • Getting Across the Cell Envelope: Mycobacterial Protein Secretion

    Woude, Aniek D. (et al.)

    Pages 109-134

Buy this book

eBook $149.00
price for USA (gross)
valid through November 5, 2017
  • ISBN 978-3-642-40232-6
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $189.00
price for USA
valid through November 5, 2017
  • ISBN 978-3-642-40231-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $189.00
price for USA
valid through November 5, 2017
  • ISBN 978-3-662-52142-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Pathogenesis of Mycobacterium tuberculosis and its Interaction with the Host Organism
Editors
  • Jean Pieters
  • John D. McKinney
Series Title
Current Topics in Microbiology and Immunology
Series Volume
374
Copyright
2013
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-40232-6
DOI
10.1007/978-3-642-40232-6
Hardcover ISBN
978-3-642-40231-9
Softcover ISBN
978-3-662-52142-7
Series ISSN
0070-217X
Edition Number
1
Number of Pages
VIII, 245
Number of Illustrations and Tables
11 b/w illustrations, 11 illustrations in colour
Topics