Antimicrobials

New and Old Molecules in the Fight Against Multi-resistant Bacteria

Editors: Marinelli, Flavia, Genilloud, Olga (Eds.)

  • Examines the latest developments in antibacterial research and drug design
  • Integrates basic and clinical aspects
  • Written by international experts
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eBook $149.00
price for USA (gross)
  • ISBN 978-3-642-39968-8
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  • Immediate eBook download after purchase
Hardcover $189.00
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  • ISBN 978-3-642-39967-1
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  • Usually dispatched within 3 to 5 business days.
Softcover $189.00
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  • ISBN 978-3-662-50908-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Reports on the emergence and prevalence of resistant bacterial infections in hospitals and communities raise concerns that we may soon no longer be able to rely on antibiotics as a way to control infectious diseases. Effective medical care would require the constant introduction of novel antibiotics to keep up in the “arms race” with resistant pathogens.

This book closely examines the latest developments in the field of antibacterial research and development. It starts with an overview of the growing prevalence of resistant Gram-positive and Gram-negative pathogens, including their various resistance mechanisms, prevalence, risk factors and therapeutic options. The focus then shifts to a comprehensive description of all major chemical classes with antibacterial properties, their chemistry, mode of action, and the generation of analogs; information that provides the basis for the design of improved molecules to defeat microbial infections and combat the emerging resistances. In closing, recently developed compounds already in clinical use, those in preclinical or first clinical studies, and a number of promising targets to be exploited in the discovery stage are discussed.

Table of contents (17 chapters)

  • The Origin and Evolution of Antibiotics

    Davies, Julian

    Pages 3-10

  • Novel Infectious Diseases and Emerging Gram-Positive Multi-Resistant Pathogens in Hospital and Community Acquired Infections

    Rossolini, Gian Maria (et al.)

    Pages 11-28

  • Gram-Negative Pathogens: Overview of Novel and Emerging Resistant Pathogens and Drugs

    Paitan, Yossi (et al.)

    Pages 29-56

  • The β-Lactam Antibiotics: Their Future in the Face of Resistance

    Leemans, Erika (et al.)

    Pages 59-84

  • Glycopeptides: An Old but Up-to-Date Successful Antibiotic Class

    Marcone, Giorgia Letizia (et al.)

    Pages 85-107

Buy this book

eBook $149.00
price for USA (gross)
  • ISBN 978-3-642-39968-8
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $189.00
price for USA
  • ISBN 978-3-642-39967-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $189.00
price for USA
  • ISBN 978-3-662-50908-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Antimicrobials
Book Subtitle
New and Old Molecules in the Fight Against Multi-resistant Bacteria
Editors
  • Flavia Marinelli
  • Olga Genilloud
Copyright
2014
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-39968-8
DOI
10.1007/978-3-642-39968-8
Hardcover ISBN
978-3-642-39967-1
Softcover ISBN
978-3-662-50908-1
Edition Number
1
Number of Pages
VIII, 364
Number of Illustrations and Tables
61 b/w illustrations, 10 illustrations in colour
Topics