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Nucleic Acids and Molecular Biology

Nucleic Acid Polymerases

Editors: Murakami, Katsuhiko, Trakselis, Michael A. (Eds.)

  • Provides a comprehensive review of the multitude of nucleic acid polymerases
  • Catalogs all nucleic acid polymerases
  • Written by polymerase fans for polymerase fans​
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eBook $129.00
price for USA (gross)
  • ISBN 978-3-642-39796-7
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $199.99
price for USA
  • ISBN 978-3-642-39795-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $169.99
price for USA
  • ISBN 978-3-662-50998-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This book provides a review of the multitude of nucleic acid polymerases, including DNA and RNA polymerases from Archea, Bacteria and Eukaryota, mitochondrial and viral polymerases, and other specialized polymerases such as telomerase, template-independent terminal nucleotidyl transferase and RNA self-replication ribozyme. Although many books cover several different types of polymerases, no book so far has attempted to catalog all nucleic acid polymerases. The goal of this book is to be the top reference work for postgraduate students, postdocs, and principle investigators who study polymerases of all varieties. In other words, this book is for polymerase fans by polymerase fans.

Nucleic acid polymerases play a fundamental role in genome replication, maintenance, gene expression and regulation. Throughout evolution these enzymes have been pivotal in transforming life towards RNA self-replicating systems as well as into more stable DNA genomes. These enzymes are generally extremely efficient and accurate in RNA transcription and DNA replication and share common kinetic and structural features. How catalysis can be so amazingly fast without loss of specificity is a question that has intrigued researchers for over 60 years. Certain specialized polymerases that play a critical role in cellular metabolism are used for diverse biotechnological applications and are therefore an essential tool for research.

Table of contents (14 chapters)

  • Introduction to Nucleic Acid Polymerases: Families, Themes, and Mechanisms

    Trakselis, Michael A. (et al.)

    Pages 1-15

  • Eukaryotic Replicative DNA Polymerases

    Walsh, Erin (et al.)

    Pages 17-41

  • DNA Repair Polymerases

    Sobol, Robert W.

    Pages 43-83

  • Eukaryotic Y-Family Polymerases: A Biochemical and Structural Perspective

    Pryor, John M. (et al.)

    Pages 85-108

  • DNA Polymerases That Perform Template-Independent DNA Synthesis

    Berdis, Anthony J.

    Pages 109-137

Buy this book

eBook $129.00
price for USA (gross)
  • ISBN 978-3-642-39796-7
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $199.99
price for USA
  • ISBN 978-3-642-39795-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $169.99
price for USA
  • ISBN 978-3-662-50998-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Nucleic Acid Polymerases
Editors
  • Katsuhiko Murakami
  • Michael A. Trakselis
Series Title
Nucleic Acids and Molecular Biology
Series Volume
30
Copyright
2014
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-39796-7
DOI
10.1007/978-3-642-39796-7
Hardcover ISBN
978-3-642-39795-0
Softcover ISBN
978-3-662-50998-2
Series ISSN
0933-1891
Edition Number
1
Number of Pages
VIII, 342
Number of Illustrations and Tables
23 b/w illustrations, 53 illustrations in colour
Topics