Development of Innovative Drugs via Modeling with MATLAB

A Practical Guide

Authors: Gieschke, Ronald, Serafin, Daniel

  • Provides concepts for the creation of drug-disease models
  • Written from the industry perspective
  • Based on many years of experience
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eBook $159.00
price for USA (gross)
  • ISBN 978-3-642-39765-3
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $209.00
price for USA
  • ISBN 978-3-642-39764-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $209.00
price for USA
  • Customers within the U.S. and Canada please contact Customer Service at 1-800-777-4643, Latin America please contact us at +1-212-460-1500 (Weekdays 8:30am – 5:30pm ET) to place your order.
  • Due: October 14, 2016
  • ISBN 978-3-662-52110-6
  • Free shipping for individuals worldwide
About this book

The development of innovative drugs is becoming more difficult while relying on empirical approaches. This inspired all major pharmaceutical companies to pursue alternative model-based paradigms. The key question is: How to find innovative compounds and, subsequently, appropriate dosage regimens?

Written from the industry perspective and based on many years of experience, this book offers:

- Concepts for creation of drug-disease models, introduced and supplemented with extensive MATLAB programs

- Guidance for exploration and modification of these programs to enhance the understanding of key principles

- Usage of differential equations to pharmacokinetic, pharmacodynamic and (patho-) physiologic problems thereby acknowledging their dynamic nature

- A range of topics from single exponential decay to adaptive dosing, from single subject exploration to clinical trial simulation, and from empirical to mechanistic disease modeling.

Students with an undergraduate mathematical background or equivalent education, interest in life sciences and skills in a high-level programming language such as MATLAB, are encouraged to engage in model-based pharmaceutical research and development.

Table of contents (9 chapters)

  • Background of Pharmacologic Modeling

    Gieschke, Ronald (et al.)

    Pages 1-20

  • First Example of a Computational Model

    Gieschke, Ronald (et al.)

    Pages 21-38

  • Differential Equations in MATLAB

    Gieschke, Ronald (et al.)

    Pages 39-85

  • Pharmacologic Modeling

    Gieschke, Ronald (et al.)

    Pages 87-141

  • Drug-Disease Modeling

    Gieschke, Ronald (et al.)

    Pages 143-205

Buy this book

eBook $159.00
price for USA (gross)
  • ISBN 978-3-642-39765-3
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $209.00
price for USA
  • ISBN 978-3-642-39764-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $209.00
price for USA
  • Customers within the U.S. and Canada please contact Customer Service at 1-800-777-4643, Latin America please contact us at +1-212-460-1500 (Weekdays 8:30am – 5:30pm ET) to place your order.
  • Due: October 14, 2016
  • ISBN 978-3-662-52110-6
  • Free shipping for individuals worldwide
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Bibliographic Information

Bibliographic Information
Book Title
Development of Innovative Drugs via Modeling with MATLAB
Book Subtitle
A Practical Guide
Authors
Copyright
2014
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-39765-3
DOI
10.1007/978-3-642-39765-3
Hardcover ISBN
978-3-642-39764-6
Softcover ISBN
978-3-662-52110-6
Edition Number
1
Number of Pages
XV, 399
Number of Illustrations and Tables
80 b/w illustrations, 112 illustrations in colour
Topics