Springer Series in Biophysics

Protein-Nanoparticle Interactions

The Bio-Nano Interface

Authors: Rahman, M., Laurent, S., Tawil, N., Yahia, L., Mahmoudi, M.

  • The first book to investigate protein-nanoparticle interactions in detail
  • Gives an overview on the applications and safety issues resulting involved
  • Written by international experts
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  • ISBN 978-3-642-37555-2
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Hardcover $139.00
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  • ISBN 978-3-642-44068-7
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About this book

In recent years, the fabrication of nanomaterials and exploration of their properties have attracted the attention of various scientific disciplines such as biology, physics, chemistry, and engineering. Although nanoparticulate systems are of significant interest in various scientific and technological areas, there is little known about the safety of these nanoscale objects. It has now been established that the surfaces of nanoparticles are immediately covered by biomolecules (e.g. proteins, ions, and enzymes) upon their entrance into a biological medium. This interaction with the biological medium modulates the surface of the nanoparticles, conferring a “biological identity” to their surfaces (referred to as a “corona”), which determines the subsequent cellular/tissue responses. The new interface between the nanoparticles and the biological medium/proteins, called “bio-nano interface,” has been very rarely studied in detail to date, though the interest in this topic is rapidly growing.

In this book, the importance of the physiochemical characteristics of nanoparticles for the properties of the protein corona is discussed in detail, followed by comprehensive descriptions of the methods for assessing the protein-nanoparticle interactions. The advantages and limitations of available corona evaluation methods (e.g. spectroscopy methods, mass spectrometry, nuclear magnetic resonance, electron microscopy, X-ray crystallography, and differential centrifugal sedimentation) are examined in detail, followed by a discussion of the possibilities for enhancing the current methods and a call for new techniques. Moreover, the advantages and disadvantages of protein-nanoparticle interaction phenomena are explored and discussed, with a focus on the biological impacts.

Table of contents (4 chapters)

  • The Biological Significance of “Nano”-interactions

    Rahman, Masoud (et al.)

    Pages 1-20

  • Nanoparticle and Protein Corona

    Rahman, Masoud (et al.)

    Pages 21-44

  • Protein Corona: Applications and Challenges

    Rahman, Masoud (et al.)

    Pages 45-63

  • Analytical Methods for Corona Evaluations

    Rahman, Masoud (et al.)

    Pages 65-82

Buy this book

eBook $109.00
price for USA (gross)
  • ISBN 978-3-642-37555-2
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $139.00
price for USA
  • ISBN 978-3-642-37554-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover n/a
  • ISBN 978-3-642-44068-7
  • Free shipping for individuals worldwide
Rent the ebook  
  • Rental duration: 1 or 6 month
  • low-cost access
  • online reader with highlighting and note-making option
  • can be used across all devices
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Bibliographic Information

Bibliographic Information
Book Title
Protein-Nanoparticle Interactions
Book Subtitle
The Bio-Nano Interface
Authors
Series Title
Springer Series in Biophysics
Series Volume
15
Copyright
2013
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-37555-2
DOI
10.1007/978-3-642-37555-2
Hardcover ISBN
978-3-642-37554-5
Softcover ISBN
978-3-642-44068-7
Series ISSN
0932-2353
Edition Number
1
Number of Pages
X, 86
Topics