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Multiscale Computer Modeling in Biomechanics and Biomedical Engineering

  • Book
  • © 2013

Overview

Editors:
  1. Amit Gefen

    1. Tel Aviv University, Department of Biomedical Engineering, Faculty of Engineering, Tel Aviv, Israel

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  • Develops computer models and simulations of the same problem at different hierarchical scales
  • Reviews the state-of-the-art in multiscale computer modeling of the current frontiers in the biosciences
  • Bridges between traditional biomedical engineering work and the newer arenas of cellular and molecular bioengineering
  • Includes supplementary material: sn.pub/extras

Part of the book series: Studies in Mechanobiology, Tissue Engineering and Biomaterials (SMTEB, volume 14)

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Table of contents (14 chapters)

  1. Front Matter

    Pages i-viii
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  2. Application of Neural Network and Finite Element Method for Multiscale Prediction of Bone Fatigue Crack Growth in Cancellous Bone

    • Ridha Hambli, Nour Hattab
    Pages 3-30

  3. Multiscale Approach to Understand the Multiphysics Phenomena in Bone Adaptation

    • Thibault Lemaire, Salah Naili
    Pages 31-72

  4. Multiscale Elastic Models of Collagen Bio-structures: From Cross-Linked Molecules to Soft Tissues

    • Michele Marino , Giuseppe Vairo
    Pages 73-102

  5. Multiscale Modeling of Ligaments and Tendons

    • Shawn P. Reese, Benjamin J. Ellis, Jeffrey A. Weiss
    Pages 103-147

  6. Multiscale Modelling of Lymphatic Drainage

    • Tiina Roose, Gavin Tabor
    Pages 149-176

  7. A Model of Electromechanical Coupling in the Small Intestine

    • Peng Du , Jeelean Lim, Leo K. Cheng
    Pages 179-207

  8. Multiscale Computational Modeling in Vascular Biology: From Molecular Mechanisms to Tissue-Level Structure and Function

    • Heather N. Hayenga, Bryan C. Thorne, Phillip Yen, Jason A. Papin, Shayn M. Peirce, Jay D. Humphrey
    Pages 209-240

  9. Multiscale Modeling in Vascular Disease and Tissue Engineering

    • Houman Zahedmanesh, Caitríona Lally
    Pages 241-258

  10. Translational Research: Multi-Scale Models of the Pulmonary Circulation in Health and Disease

    • Alys R. Clark, Kelly S. Burrowes, Merryn H. Tawhai
    Pages 259-286

  11. A Multilevel Finite Element Approach to Study Pressure Ulcer Aetiology

    • Cees W. J. Oomens
    Pages 289-298

  12. Discrete and Continuum Multiscale Behaviour in Bacterial Communication

    • Sara Jabbari, John R. King
    Pages 299-320

  13. Wound Healing: Multi-Scale Modeling

    • Fred J. Vermolen, Amit Gefen
    Pages 321-345

  14. Modeling Multiscale Necrotic and Calcified Tissue Biomechanics in Cancer Patients: Application to Ductal Carcinoma In Situ (DCIS)

    • Paul Macklin, Shannon Mumenthaler, John Lowengrub
    Pages 349-380

  15. Integration of Molecular Signaling into Multiscale Modeling of Cancer

    • Zhihui Wang, Vittorio Cristini
    Pages 381-394

  16. Back Matter

    Pages 395-396
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Keywords

About this book

This book reviews the state-of-the-art in multiscale computer modeling, in terms of both accomplishments and challenges. The information in the book is particularly useful for biomedical engineers, medical physicists and researchers in systems biology, mathematical biology, micro-biomechanics and biomaterials who are interested in how to bridge between traditional biomedical engineering work at the organ and tissue scales, and the newer arenas of cellular and molecular bioengineering.

Editors and Affiliations

  • Tel Aviv University, Department of Biomedical Engineering, Faculty of Engineering, Tel Aviv, Israel

    Amit Gefen

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