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Evolution of Extracellular Matrix

  • Book
  • © 2013

Overview

Editors:
  1. Fred W. Keeley

    1. Hospital for Sick Children, Toronto, Canada

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    You can also search for this editor in PubMed   Google Scholar

  2. Robert P. Mecham

    1. Dept. Cell Biology & Physiology, Washington University School of Medicine, St. Louis, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Gives a comprehensive and up to date overview on the field
  • Written by experts in the field
  • First book to look in detail on the evolution of ECM
  • Includes supplementary material: sn.pub/extras

Part of the book series: Biology of Extracellular Matrix (BEM)

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Table of contents (10 chapters)

  1. Front Matter

    Pages i-x
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  2. Extracellular Matrix Evolution: An Overview

    • Josephine C. Adams
    Pages 1-25

  3. Domain Shuffling and the Evolution of Vertebrate Extracellular Matrix

    • Hiroshi Wada
    Pages 27-37

  4. Invertebrate and Vertebrate Collagens

    • Jean-Yves Exposito, Claire Lethias
    Pages 39-72

  5. The Evolution of Elastin

    • Fred W. Keeley
    Pages 73-119

  6. Evolutionary Insights into Fibrillin Structure and Function in the Extracellular Matrix

    • Sacha Jensen, David Yadin, Ian Robertson, Penny Handford
    Pages 121-162

  7. Molecular Evolution of the Microfibril-Associated Proteins: The Fibulins and the MAGPs

    • Fernando Segade
    Pages 163-190

  8. Evolution and Function of SPARC and Tenascins: Matricellular Counter-Adhesive Glycoproteins with Pleiotropic Effects on Angiogenesis and Tissue Fibrosis

    • Cristina A. Baratta, Theodore J. Brown, Fahd Al-Dhalaan, Maurice J. Ringuette
    Pages 191-220

  9. Thrombospondins and Their Receptors: Evolving Functions

    • David D. Roberts, William A. Frazier
    Pages 221-242

  10. Evolution of Cell Adhesion to Extracellular Matrix

    • Mark S. Johnson, Jarmo Käpylä, Konstantin Denessiouk, Tomi Airenne, Bhanupratap Singh Chouhan, Jyrki Heino
    Pages 243-283

  11. Erratum to: Evolution of Cell Adhesion to Extracellular Matrix

    • Mark S. Johnson, Jarmo Käpylä, Konstantin Denessiouk, Tomi Airenne, Bhanupratap Singh Chouhan, Jyrki Heino
    Pages E1-E5

  12. Back Matter

    Pages 285-290
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Keywords

About this book

The evolution of single cells into multicellular organisms was mediated, in large part, by the extracellular matrix. The proteins and glycoconjugates that make up the extracellular matrix provide structural support to cellular complexes, facilitate cell adhesion and migration, and impart mechanical properties that are important for tissue function. Each class of ECM macromolecule has evolved to incorporate distinctive properties that are defined by conserved modules that are mixed together to achieve appropriate function.  This volume provides a comprehensive analysis of how the major ECM components evolved over time in order to fill their specific roles found in modern organisms. The major focus is on the structural matrix proteins, matricellular proteins, and more complex ECM structures such as basement membranes. Adhesive proteins and their receptors are also discussed.

Editors and Affiliations

  • Hospital for Sick Children, Toronto, Canada

    Fred W. Keeley

  • Dept. Cell Biology & Physiology, Washington University School of Medicine, St. Louis, USA

    Robert P. Mecham

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