Current Topics in Microbiology and Immunology

New Perspectives in Regeneration

Editors: Heber-Katz, Ellen, Stocum, David L. (Eds.)

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About this book

Regeneration, the homeostatic ability to maintain tissue structure in the face of normal cell turnover or loss of tissue damaged by trauma or disease, is an essential developmental process that continues throughout life. As recently as a decade ago, any serious discussion of the possibility of regeneration becoming a practical medical tool in the near future had the air of science fiction or over-optimistic speculation. The term “regenerative medicine” was certainly on many lips but few actually expected to soon see it applied in a clinical setting. A tidal wave of discovery has changed that and investigating the cellular mechanisms of natural regeneration has become one of the hottest topics in developmental biology and biomedicine in general. Many researchers entering the field find that the regeneration literature is still quite diffuse perhaps owing to the disparate biological systems that have been the object of study including hydra, planaria, newts, axolotls and more recently several mouse strains. The volume editors believe that an attempt to organize or systematize the literature is long overdue. In this volume, respected experts highlight the latest findings in vertebrate (including mammals) wound healing and regeneration. They present eleven reviews that cover a wide range of topics, from wound repair and its relationship to regeneration, through systems including lenticular, neural, and musculoskeletal tissues and limbs, to epigenetics and the role of the cell cycle. Nuclear reprogramming and cellular plasticity, which open the door for potential regenerative medical therapies for injury and degenerative disease, are recurring themes throughout the book. We are all now part of the regeneration revolution.

Reviews

“This is an outstanding textbook about limb bud regeneration into fully functional limbs in fish, mammals, and amphibian species. … The operative signaling including full color microscopic images and diagrams is provided. I highly commend it for all devoted scientists.” (Joseph J. Grenier, Amazon.com, September, 2015) 


Table of contents (11 chapters)

  • Mechanisms of Vessel Regression: Toward an Understanding of the Resolution of Angiogenesis

    Wietecha, Mateusz S. (et al.)

    Pages 3-32

  • Wound Healing in Mammals and Amphibians: Toward Limb Regeneration in Mammals

    Kawasumi, Aiko (et al.)

    Pages 33-49

  • Cellular Plasticity During Vertebrate Appendage Regeneration

    Monaghan, James R. (et al.)

    Pages 53-74

  • Cell Signaling Pathways in Vertebrate Lens Regeneration

    Henry, Jonathan J. (et al.)

    Pages 75-98

  • Regenerative Medicine: Challenges and Perspectives for Successful Therapies

    Viswanathan, S. (et al.)

    Pages 101-112

Buy this book

eBook $169.00
price for USA (gross)
  • ISBN 978-3-642-35810-4
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.00
price for USA
  • ISBN 978-3-642-35809-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $219.00
price for USA
  • ISBN 978-3-642-43081-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
New Perspectives in Regeneration
Editors
  • Ellen Heber-Katz
  • David L. Stocum
Series Title
Current Topics in Microbiology and Immunology
Series Volume
367
Copyright
2013
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-35810-4
DOI
10.1007/978-3-642-35810-4
Hardcover ISBN
978-3-642-35809-8
Softcover ISBN
978-3-642-43081-7
Series ISSN
0070-217X
Edition Number
1
Number of Pages
X, 281
Topics