Regulatory Toxicology

Editors: Reichl, Franz-Xaver, Schwenk, Michael (Eds.)

  • Provides a unique reference work on the process of toxicological risk assessment, from cell to population
  • Describes experimental methods and scientific approaches in an accessible way for all those involved in toxicological data generation and decision-making
  • Covers modern test systems, basic risk concepts and the concepts employed by regulatory agencies, industry and academia
  • Presents expert insights on data collection, extrapolation and estimation in toxicology
see more benefits

Buy this book

Print $699.99
price for USA
  • ISBN 978-3-642-35373-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Print + eBook $929.00
price for USA
  • ISBN 978-3-642-35375-8
  • Free shipping for individuals worldwide
  • Online orders shipping within 2-3 days.
eReference $619.00
price for USA (gross)
  • ISBN 978-3-642-35374-1
  • Free shipping for individuals worldwide
About this Reference Work

This book will be written by experts for professionals, scientists and all those involved in toxicological data generation and decision-making. It is the updated and expanded version of a monograph published in German in 2004.  Chemical safety is regulated on various levels including production, storage, transport, handling, disposal or labelling. This book deals comprehensively with the safety-ensuring methods and concepts employed by regulatory agencies, industry and academics. Toxicologists use experimental and scientific approaches for data collection, e.g. about chemical hazards, physicochemical features or toxicokinetics. The respective experimental methods are described in the book. Toxicologists also deal with much insecurity in the exposure and effect scenarios during risk assessment. To overcome these, they have different extrapolation methods and estimation procedures at their disposal. The book describes these methods in an accessible manner. Differing concepts from one regulation area to another are also covered. Reasons and consequences become evident when reading the book. Altogether, the book Regulatory Toxicology will serve as an excellent reference.

About the authors

Franz-Xaver Reichl studied Microbiology and Medicine in Munich, Germany. He is Head of the Department of Dental Toxicology at the Department of Operative/Restorative Dentistry, Periodontology and Pedodontics, LMU Munich and Head of the International Advisory Centre for the toxicology and biocompatibility of dental materials. His field of research cover studies on cytotoxic, mutagenic, carcinogenic and embryotoxic effects of chemical compounds (e.g. dental materials) in human and animal cells, abrasion of composites and elution of dental composite components during the chewing situation in the chewing simulator MUC/3 and in vitro- and in vivo studies on toxicokinetic and toxicodynamic effects of chemical compounds (e.g. dental materials). He also work on studies on the pathways and on the analysis of intermediates in the metabolism of dental composite components in biological systems and risk assessments of xenobiotics (e.g. dental materials). Michael Schwenk studied Biochemistry and Medicine in Tuebingen, Germany. He then qualifiedas a toxicologist and pharmacologist and worked in universities, industry and a health agency. He initially focused on experimental cell toxicology, but later shifted to the measurement of chemical residues in humans and to study the health effects of such exposures in different populations. He was active in various national regulatory committees, advised the colleagues of the public health service of Baden-Württemberg and received practical experience in all major areas of regulatory toxicology.

Video

Table of contents (80 chapters)

  • Aims and Mission of Regulatory Toxicology

    Greim, Helmut

    Pages 3-20

  • Working Areas of Regulatory Toxicology

    Schwenk, Michael (et al.)

    Pages 21-30

  • National and International Collaboration in Regulatory Toxicology

    Appel, Klaus E.

    Pages 31-47

  • The Regulatory Process in Toxicology

    Henschler, Dietrich (et al.)

    Pages 49-55

  • Quality Assurance in Regulatory Toxicology

    Lilienblum, Werner (et al.)

    Pages 57-63

Buy this book

Print $699.99
price for USA
  • ISBN 978-3-642-35373-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Print + eBook $929.00
price for USA
  • ISBN 978-3-642-35375-8
  • Free shipping for individuals worldwide
  • Online orders shipping within 2-3 days.
eReference $619.00
price for USA (gross)
  • ISBN 978-3-642-35374-1
  • Free shipping for individuals worldwide
Loading...

Recommended for you

Loading...

Bibliographic Information

Bibliographic Information
Book Title
Regulatory Toxicology
Editors
  • Franz-Xaver Reichl
  • Michael Schwenk
Copyright
2014
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
Print ISBN
978-3-642-35373-4
Print + eBook ISBN
978-3-642-35375-8
eReference ISBN
978-3-642-35374-1
Edition Number
1
Number of Pages
XXIV, 946
Number of Illustrations and Tables
74 b/w illustrations, 70 illustrations in colour
Additional Information
Based on the German edition "Regulatorische Toxikologie" (2004) but revised, updated and supplemented; approx. 80 authors with international co-authors
Topics