Research and Perspectives in Endocrine Interactions

Multiple Origins of Sex Differences in Brain

Neuroendocrine Functions and their Pathologies

Editors: Pfaff, Donald W, Christen, Yves (Eds.)

  • Latest research on epigenetics and brain development
  • Presents animal and human studies
  • Written by leading international experts in the field    
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eBook $169.00
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  • ISBN 978-3-642-33721-5
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Hardcover $219.00
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  • ISBN 978-3-642-33720-8
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About this book

In theoretical terms, sex differences in brains and behaviors of laboratory animals offer the possibility of fascinating scientific studies on a range of molecular phenomena such as genomic imprinting, DNA methylation, chromatin protein modification, non-coding DNA, potentially resulting in important neuroanatomical and neurochemical sex differences in the brain. Such sex differences could arise consequent to exposures to testosterone early in development, or to other effects deriving from the Y chromosome. However, this general subject has been treated with much hyperbole. Historically, sex differences were assumed to be present where they did not really exist, e.g. with respect to mathematics, executive leadership, etc. etc. Under what circumstances do we really care about sex differences in brain and behavior? These circumstances concern human maladies whose diagnoses are much different between boys and girls, or between women and men. Prominent examples discussed in this volume include autism, attention deficit hyperactivity disorders and congenital adrenal hyperplasia. In fact, infant boys are more susceptible than infant girls to a variety of disorders that arise early in development. This volume then ends with a consideration of effects of estrogenic hormones on the injured brain, and their roles as protective agents.

Table of contents (11 chapters)

  • Hormone-Dependent Chromatin Modifications Related to Sexually Differentiated Behaviors

    Gagnidze, Khatuna (et al.)

    Pages 1-19

  • Importance of Genomic Imprinting in the Evolution and Development of the Maternal Brain

    Keverne, Barry E.

    Pages 21-33

  • Genomic Imprinting in the Adult and Developing Brain

    Dulac, Catherine (et al.)

    Pages 35-41

  • The Synapse: Differences Between Men and Women

    DeFelipe, Javier (et al.)

    Pages 43-57

  • Gonadal Hormone Influences on Human Neurobehavioral Development: Outcomes and Mechanisms

    Hines, Melissa

    Pages 59-69

Buy this book

eBook $169.00
price for USA (gross)
valid through November 5, 2017
  • ISBN 978-3-642-33721-5
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.00
price for USA
valid through November 5, 2017
  • ISBN 978-3-642-33720-8
  • Free shipping for individuals worldwide
  • Online orders shipping within 2-3 days.
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Bibliographic Information

Bibliographic Information
Book Title
Multiple Origins of Sex Differences in Brain
Book Subtitle
Neuroendocrine Functions and their Pathologies
Editors
  • Donald W Pfaff
  • Yves Christen
Series Title
Research and Perspectives in Endocrine Interactions
Copyright
2013
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-33721-5
DOI
10.1007/978-3-642-33721-5
Hardcover ISBN
978-3-642-33720-8
Series ISSN
1861-2253
Edition Number
1
Number of Pages
XIII, 181
Topics