Advances in Anatomy, Embryology and Cell Biology

Stimulation of Trigeminal Afferents Improves Motor Recovery After Facial Nerve Injury

Functional, Electrophysiological and Morphological Proofs

Authors: Skouras, E., Pavlov, S., Bendella, H., Angelov, D.N.

  • The recovery of mimic function after facial nerve transection is still poor and research for better results much needed
  • Written by experts in facial nerve reconstruction with immediate potential for clinical rehabilitation following facial nerve reconstruction
  • D.N.Angelov is a well known author in this field
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About this book

Recovery of mimic function after facial nerve transection is poor: the successful regrowth of axotomized motoneurons to their targets is compromised by (i) poor axonal navigation and excessive collateral branching, (ii) abnormal exchange of nerve impulses between adjacent regrowing axons and (iii) insufficient synaptic input to facial motoneurons. As a result, axotomized motoneurons get hyperexcitable and unable to discharge. Since improvement of growth cone navigation and reduction of the ephaptic cross-talk between axons turn out be very difficult, the authorsa concentrated on the third detrimental component and proposed that an intensification of the trigeminal input to axotomized electrophysiologically silent facial motoneurons might improve specificity of reinnervation. To test the hypothesis they compared behavioral, electrophysiological and morphological parameters after single reconstructive surgery on the facial nerve with those obtained after identical facial nerve surgery, but combined with direct or indirect stimulation of the ipsilateral infraorbital (ION) nerve.  The authors found that in all cases trigeminal stimulation was beneficial for the outcome by improving the quality of target reinnervation and recovery of vibrissal motor performance.

Table of contents (5 chapters)

Buy this book

eBook $119.00
price for USA (gross)
valid through November 5, 2017
  • ISBN 978-3-642-33311-8
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $159.00
price for USA
valid through November 5, 2017
  • ISBN 978-3-642-33310-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Rent the eBook  
  • Rental duration: 1 or 6 month
  • low-cost access
  • online reader with highlighting and note-making option
  • can be used across all devices
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Bibliographic Information

Bibliographic Information
Book Title
Stimulation of Trigeminal Afferents Improves Motor Recovery After Facial Nerve Injury
Book Subtitle
Functional, Electrophysiological and Morphological Proofs
Authors
Series Title
Advances in Anatomy, Embryology and Cell Biology
Series Volume
213
Copyright
2013
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-33311-8
DOI
10.1007/978-3-642-33311-8
Softcover ISBN
978-3-642-33310-1
Series ISSN
0301-5556
Edition Number
1
Number of Pages
XV, 110
Topics