Springer Theses

Novel Synthetic Chemistry of Ureas and Amides

Authors: Hutchby, Marc

  • Nominated by the University of Bristol as an outstanding PhD thesis
  • New method for breaking urea and amide bonds outlined
  • Far reaching consequences for the study of biological protein manipulation
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  • ISBN 978-3-642-32051-4
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Softcover $129.00
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  • ISBN 978-3-642-44890-4
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About this book

In this thesis, the author investigates the chemistry and application of molecules containing urea and amide bonds. These bonds are some of the strongest known and are fundamental to biological processes. The author describes his discovery that sterically hindered ureas undergo solvolysis at room temperature under neutral conditions. This is a remarkable finding, since ureas are inert under these conditions and a general rule of chemistry is that hindered substrates are less reactive. Remarkably, the author translates these results to the correspondingly sterically hindered amides. This thesis has resulted in a number of outstanding publications in high profile journals. The unique method for breaking urea and amide bonds developed in this study is likely to have far reaching consequences for biological protein manipulation.

Table of contents (7 chapters)

Buy this book

eBook $99.00
price for USA (gross)
  • ISBN 978-3-642-32051-4
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $129.00
price for USA
  • ISBN 978-3-642-32050-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $129.00
price for USA
  • ISBN 978-3-642-44890-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Novel Synthetic Chemistry of Ureas and Amides
Authors
Series Title
Springer Theses
Copyright
2013
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-32051-4
DOI
10.1007/978-3-642-32051-4
Hardcover ISBN
978-3-642-32050-7
Softcover ISBN
978-3-642-44890-4
Series ISSN
2190-5053
Edition Number
1
Number of Pages
XVIII, 166
Topics